CymitQuimica logo

CAS 18361-48-3

:

Leucomycin A6

Description:
Leucomycin A6 is a macrolide antibiotic that is derived from the fermentation of the bacterium *Streptomyces aureofaciens*. It is characterized by its complex structure, which includes a large lactone ring and multiple sugar moieties, contributing to its biological activity. This compound exhibits antibacterial properties, particularly against Gram-positive bacteria, making it effective in treating various infections. Leucomycin A6 functions by inhibiting bacterial protein synthesis, specifically targeting the 50S ribosomal subunit, which disrupts the translation process. It is often used in clinical settings for patients who are allergic to penicillin or when penicillin is ineffective. The compound is known for its stability in acidic conditions, which enhances its bioavailability. However, like many antibiotics, it can lead to resistance if misused. Its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are important for determining appropriate dosing regimens. Overall, Leucomycin A6 is a significant antibiotic with specific applications in treating bacterial infections, particularly in cases where alternative treatments are necessary.
Formula:C40H65NO15
InChI:InChI=1/C40H65NO15/c1-11-30(45)54-38-25(5)51-32(21-40(38,7)48)55-35-24(4)52-39(34(47)33(35)41(8)9)56-36-27(17-18-42)19-22(2)28(44)16-14-12-13-15-23(3)50-31(46)20-29(37(36)49-10)53-26(6)43/h12-14,16,18,22-25,27-29,32-39,44,47-48H,11,15,17,19-21H2,1-10H3/b13-12+,16-14+
Synonyms:
  • Leukomycin A6
  • Leucomycin V, 3-acetate 4B-propanoate
  • Yl 704 B3
  • Oxacyclohexadecane, leucomycin V deriv.
  • Leucomycin V, 3-acetate 4(sup B)-propanoate
  • Antibiotic YL 704B3
  • Leucomycin A6
  • (2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6S)-6-{[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-4-(acetyloxy)-10-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy-2-methyltetrahydro-2H-pyran-3-yl]oxy}-4-hydroxy-2,4-dimethyltetrahydro-2H-pyran-3-yl propanoate (non-preferred name)
  • Turimycin A3
  • Platenomycin-B3
  • See more synonyms
Sort by
The purity filter is not visible because current products do not have associated purity data for filtering.
Found 2 products.