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CAS 18361-49-4

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Leucomycin A9

Description:
Leucomycin A9 is a macrolide antibiotic that is derived from the fermentation of the bacterium *Streptomyces aureofaciens*. It is characterized by its complex structure, which includes a large lactone ring and multiple sugar moieties, contributing to its biological activity. This compound exhibits antibacterial properties, particularly against Gram-positive bacteria, making it useful in treating various infections. Leucomycin A9 functions by inhibiting bacterial protein synthesis, thereby preventing the growth and reproduction of susceptible microorganisms. Its mechanism of action is similar to that of other macrolides, such as erythromycin. The substance is typically administered in clinical settings and may be used in combination with other antibiotics to enhance therapeutic efficacy. Additionally, it is important to consider its pharmacokinetics, potential side effects, and resistance patterns when evaluating its clinical use. As with many antibiotics, the emergence of resistant strains necessitates careful monitoring and judicious use to maintain its effectiveness in treating bacterial infections.
Formula:C37H61NO14
InChI:InChI=1S/C37H61NO14/c1-20-17-25(15-16-39)33(34(46-9)27(42)18-28(43)47-21(2)13-11-10-12-14-26(20)41)52-36-31(44)30(38(7)8)32(22(3)49-36)51-29-19-37(6,45)35(23(4)48-29)50-24(5)40/h10-12,14,16,20-23,25-27,29-36,41-42,44-45H,13,15,17-19H2,1-9H3/b11-10+,14-12+/t20-,21-,22-,23+,25+,26+,27-,29+,30-,31-,32-,33+,34+,35+,36+,37-/m1/s1
InChI key:InChIKey=LOJFCOBMHWVESZ-MXYURFFASA-N
SMILES:O([C@H]1[C@@H](CC=O)C[C@@H](C)[C@@H](O)/C=C/C=C/C[C@@H](C)OC(=O)C[C@@H](O)[C@@H]1OC)[C@H]2[C@H](O)[C@@H](N(C)C)[C@H](O[C@H]3C[C@@](C)(O)[C@@H](OC(C)=O)[C@H](C)O3)[C@@H](C)O2
Synonyms:
  • Leucomycin V, 4B-acetate
  • Leucomycin A9
  • Oxacyclohexadecane, leucomycin V deriv.
  • Turimycin H2
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