CAS: 18378-89-7 - Mithramycin

Formula: C₅₂H₇₆O₂₄

InChI: InChI=1S/C52H76O24/c1-18-29(72-34-14-30(43(58)21(4)68-34)73-33-13-28(54)42(57)20(3)67-33)12-26-10-25-11-27(49(66-9)48(63)41(56)19(2)53)50(47(62)39(25)46(61)38(26)40(18)55)76-36-16-31(44(59)23(6)70-36)74-35-15-32(45(60)22(5)69-35)75-37-17-52(8,65)51(64)24(7)71-37/h10,12,19-24,27-28,30-37,41-45,49-51,53-61,64-65H,11,13-17H2,1-9H3/t19-,20-,21-,22-,23-,24-,27+,28-,30-,31-,32-,33+,34+,35+,36+,37+,41+,42-,43-,44-,45+,49+,50+,51-,52+/m1/s1

InChI key: InChIKey=CFCUWKMKBJTWLW-BKHRDMLASA-N

SMILES: O=C1C2=C(O)C3=C(O)C(=C(OC4OC(C)C(O)C(OC5OC(C)C(O)C(O)C5)C4)C=C3C=C2CC(C1OC6OC(C)C(O)C(OC7OC(C)C(O)C(OC8OC(C)C(O)C(O)(C)C8)C7)C6)C(OC)C(=O)C(O)C(O)C)C

Synonyms:

• <span class="text-smallcaps">D</smallcap>-threo-2-Pentulose, 5-deoxy-1-C-[(2S,3S)-7-[[2,6-dideoxy-3-O-(2,6-dideoxy-β-<smallcap>D</smallcap>-arabino-hexopyranosyl)-β-<smallcap>D</smallcap>-arabino-hexopyranosyl]oxy]-3-[(O-2,6-dideoxy-3-C-methyl-β-<smallcap>D</smallcap>-ribo-hexopyranosyl-(1→3)-O-2,6-dideoxy-β-<smallcap>D</smallcap>-lyxo-hexopyranosyl-(1→3)-2,6-dideoxy-β-<smallcap>D</span>-arabino-hexopyranosyl)oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-1-O-methyl-, (1S)-
• A 2371
• Antibiotic LA 7017
• Aureolic acid
• Mithracin
• Mithramycin
• Mithramycin A
• Mitramycin
• Nsc 24559
• Pa 144
• Plicamycin
• Plicatomycin
• [1S(2S,3S)]-5-Deoxy-1-C-[7-[[2,6-dideoxy-3-O-(2,6-dideoxy-β-<span class="text-smallcaps">D</smallcap>-arabino-hexopyranosyl)-β-<smallcap>D</smallcap>-arabino-hexopyranosyl]oxy]-3-[(O-2,6-dideoxy-3-C-methyl-β-<smallcap>D</smallcap>-ribo-hexopyranosyl-(1→3)-O-2,6-dideoxy-β-<smallcap>D</smallcap>-arabino-hexopyranosyl-(1→3)-2,6-dideoxy-β-<smallcap>D</smallcap>-lyxo-hexopyranosyl)oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-1-O-methyl-<smallcap>D</span>-threo-2-pentulose
• [1S(2S,3S)]-5-Deoxy-1-C-[7-[[2,6-dideoxy-3-O-(2,6-dideoxy-β-D-arabino-hexopyranosyl)-β-D-arabino-hexopyranosyl]oxy]-3-[(O-2,6-dideoxy-3-C-methyl-β-D-ribo-hexopyranosyl-(1→3)-O-2,6-dideoxy-β-D-arabino-hexopyranosyl-(1→3)-2,6-dideoxy-β-D-lyxo-hexopyranosyl)oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-1-O-methyl-D-threo-2-pentulose
• D-threo-2-Pentulose, 5-deoxy-1-C-[(2S,3S)-7-[[2,6-dideoxy-3-O-(2,6-dideoxy-β-D-arabino-hexopyranosyl)-β-D-arabino-hexopyranosyl]oxy]-3-[(O-2,6-dideoxy-3-C-methyl-β-D-ribo-hexopyranosyl-(1→3)-O-2,6-dideoxy-β-D-lyxo-hexopyranosyl-(1→3)-2,6-dideoxy-β-D-arabino-hexopyranosyl)oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-1-O-methyl-, (1S)-

Plicamycin

CAS: 18378-89-7

• Formula: C₅₂H₇₆O₂₄
• Purity: %
• Color and Shape: Solid
• Molecular weight: 1085.1454

Mithramycin A

CAS: 18378-89-7

• Formula: C₅₂H₇₆O₂₄
• Purity: ≥ 98.0%
• Color and Shape: Yellow powder
• Molecular weight: 1085.15

Mithramycin A

CAS: 18378-89-7

Mithramycin A (Plicamycin), a DNA-binding antitumor antibiotic, is a selective specificity protein 1 (Sp1) inhibitor, …

• Formula: C₅₂H₇₆O₂₄
• Purity: 99.28%
• Color and Shape: Yellow Powder
• Molecular weight: 1085.15

Mithramycin A from Streptomyces argillaceus

CAS: 18378-89-7

• Formula: C₅₂H₇₆O₂₄
• Purity: By hplc: 98.0% (Typical Value in Batch COA)
• Color and Shape: yellow powder
• Molecular weight: 1,085.15g/mol

Mithramycin A

CAS: 18378-89-7

Applications Mithramycin A is an anticancer antibiotic that selectively binds to G-C-rich DNA in the …

• Formula: C₅₂H₇₆O₂₄
• Color and Shape: Yellow Crystalline Powder
• Molecular weight: 1085.15

Mithramycin A

CAS: 18378-89-7

Antineoplastic antibiotic; RNA synthesis inhibitor

• Formula: C₅₂H₇₆O₂₄
• Purity: Min. 95%
• Color and Shape: Yellow Powder
• Molecular weight: 1,085.15 g/mol