CAS 183849-43-6

ABAPERIDONE

Description:

Abaperidone is a chemical compound classified as an atypical antipsychotic agent. It is primarily characterized by its ability to modulate neurotransmitter activity in the brain, particularly affecting dopamine and serotonin receptors. This modulation is crucial for its therapeutic effects in treating psychiatric disorders, such as schizophrenia. Abaperidone exhibits a unique chemical structure that contributes to its pharmacological profile, including a specific arrangement of functional groups that enhance its binding affinity to target receptors. The compound is typically administered in a controlled dosage form, and its pharmacokinetics involve absorption, distribution, metabolism, and excretion processes that are essential for its efficacy and safety. Additionally, like many antipsychotics, abaperidone may have side effects, which necessitate careful monitoring during treatment. Overall, its development represents a significant advancement in the search for effective treatments for mental health conditions, aiming to improve patient outcomes while minimizing adverse effects.

Formula: C₂₅H₂₅FN₂O₅

InChI: InChI=1/C25H25FN2O5/c26-18-2-4-20-23(12-18)33-27-24(20)16-6-9-28(10-7-16)8-1-11-31-19-3-5-21-22(13-19)32-15-17(14-29)25(21)30/h2-5,12-13,15-16,29H,1,6-11,14H2

SMILES: C(CN1CCC(CC1)c1c2ccc(cc2on1)F)COc1ccc2c(c1)occ(CO)c2=O

Synonyms:

• Abaperidone [INN]
• 7-(3-(4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperidino)propoxy)-3-(hydroxymethyl)-4H-1-benzopyran-4-one
• Fi-8602
• Unii-40755Z8956
• 7-{3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl]propoxy}-3-(hydroxymethyl)-4H-chromen-4-one

Abaperidone

CAS: 183849-43-6

Abaperidone

Purity: ≥90%

Molecular weight: 452.47g/mol

Ref: 54-BUP04900

Abaperidone

CAS: 183849-43-6

Abaperidone is a drug that is used to treat the symptoms of bowel disease, such as inflammation and ulceration. It inhibits the action of 5-hydroxytryptamine (5-HT) at neuronal 5-HT2 receptors in the brain and gastrointestinal tract. Abaperidone also inhibits the activity of gamma-aminobutyric acid (GABA) at GABA receptors in the brain and gastrointestinal tract, which may be useful for treating bowel disease. Abaperidone has been shown to have no significant effect on serum prolactin levels in humans.

Formula: C₂₅H₂₅FN₂O₅

Purity: Min. 95%

Molecular weight: 452.5 g/mol

Ref: 3D-IHA84943

Abaperidone

CAS: 183849-43-6

Abaperidone is an atypical antipsychotic, antagonizes 5-HT2A (IC50=6.2 nM) and D2 receptors (IC50=17 nM), reduces hsp70 mRNA in rat brains.

Formula: C₂₅H₂₅FN₂O₅

Purity: 99.77%

Color and Shape: Solid

Molecular weight: 452.47

Ref: TM-T14083