CAS 18385-59-6

Epoxyazadiradione

Description:

Epoxyazadiradione, with the CAS number 18385-59-6, is a chemical compound derived from the neem tree (Azadirachta indica), known for its various biological activities. This compound is characterized by its unique molecular structure, which includes an epoxy group, contributing to its reactivity and potential applications in various fields. Epoxyazadiradione exhibits insecticidal and antifungal properties, making it of interest in agricultural and pest management contexts. Its mechanism of action often involves disrupting the hormonal systems of insects, leading to growth inhibition and mortality. Additionally, it has been studied for its potential therapeutic effects, including anti-inflammatory and antioxidant activities. The compound is typically found in low concentrations in neem extracts, and its efficacy can be influenced by factors such as formulation and application methods. As with many natural products, further research is ongoing to fully understand its properties, mechanisms, and potential uses in both agriculture and medicine.

Formula: C₂₈H₃₄O₆

InChI: InChI=1/C28H34O6/c1-15(29)33-20-13-18-24(2,3)19(30)8-10-25(18,4)17-7-11-26(5)21(16-9-12-32-14-16)22(31)23-28(26,34-23)27(17,20)6/h8-10,12,14,17-18,20-21,23H,7,11,13H2,1-6H3/t17-,18+,20?,21?,23-,25-,26?,27+,28-/m1/s1

InChI key: InChIKey=NEYCGDYQBQONFC-GGPFZBFUSA-N

SMILES: C[C@]12[C@]34[C@](C)([C@@H](C(=O)[C@]3(O4)[H])C=5C=COC5)CC[C@@]1([C@]6(C)[C@@](C[C@H]2OC(C)=O)(C(C)(C)C(=O)C=C6)[H])[H]

Synonyms:

• (5Alpha,13Xi,14Beta,15Beta)-17-(Furan-3-Yl)-4,4,8-Trimethyl-3,16-Dioxo-14,15-Epoxyandrost-1-En-7-Yl Acetate
• (5alpha,7alpha,13alpha,14beta,15beta,17alpha)-7-(Acetyloxy)-14,15:21,23-diepoxy-4,4,8-trimethyl-24-norchola-1,20,22-triene-3,16-dione
• (5α,7α,13α,14β,15β,17α)-7-(Acetyloxy)-14,15:21,23-diepoxy-4,4,8-trimethyl-24-norchola-1,20,22-triene-3,16-dione
• 14,15-Epoxy-14H-cyclopenta[a]phenanthrene, 24-norchola-1,20,22-triene-3,16-dione deriv.
• 24-Nor-5α,13α,14β,17α-chola-1,20,22-triene-3,16-dione, 14,15β:21,23-diepoxy-7α-hydroxy-4,4,8-trimethyl-, acetate
• 24-Norchola-1,20,22-triene-3,16-dione, 7-(acetyloxy)-14,15:21,23-diepoxy-4,4,8-trimethyl-, (5alpha,7alpha,13alpha,14beta,15beta,17alpha)-
• 24-Norchola-1,20,22-triene-3,16-dione, 7-(acetyloxy)-14,15:21,23-diepoxy-4,4,8-trimethyl-, (5α,7α,13α,14β,15β,17α)-
• Azadiradione 14β,15β-epoxide
• Azadiradione, epoxy-
• Nimbinin
• Nsc 640467
• Epoxyazadiradione

Epoxyazadiradione

CAS: 18385-59-6

Epoxyazadiradione

Purity: ≥98%

Molecular weight: 466.57g/mol

Ref: 54-BUP02991

Epoxyazadiradione

CAS: 18385-59-6

Epoxyazadiradione, from Neem, may trigger apoptosis and block NF-kB in cervical cancer cells.

Formula: C₂₈H₃₄O₆

Purity: 99.29%

Color and Shape: Solid

Molecular weight: 466.57

Ref: TM-TN6730

14,15-Epoxy-Azadiradione

CAS: 18385-59-6

Formula: C₂₈H₃₄O₆

Molecular weight: 466.57

Ref: 4Z-A-380002

Epoxyazadiradione

Controlled Product

CAS: 18385-59-6

Applications Epoxyazadiradione is an extract from Neem (Azadirachta indica) plant and may induce mitochondrial apoptosis and inhibition of NFkB in human cervical cancer cells.
References Shilpa, G. et al.: Phytother. Res., 31, 1892 (2017);

Formula: C₂₈H₃₄O₆

Color and Shape: Off-White

Molecular weight: 466.56

Ref: TR-E590018

Epoxyazadiradione

CAS: 18385-59-6

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Formula: C₂₈H₃₄O₆

Purity: Min. 95%

Molecular weight: 466.6 g/mol

Ref: 3D-TAA38559