CAS 18388-03-9

2-Chloromethyl-3-trimethylsilyl-1-propene

Description:

2-Chloromethyl-3-trimethylsilyl-1-propene is an organosilicon compound characterized by the presence of both a chloromethyl group and a trimethylsilyl group attached to a propene backbone. This compound typically exhibits a colorless to pale yellow liquid form, with a distinctive odor. Its structure includes a vinyl group, which contributes to its reactivity, particularly in addition reactions and polymerization processes. The presence of the chloromethyl group makes it a potential electrophile, allowing it to participate in nucleophilic substitution reactions. The trimethylsilyl group enhances its stability and solubility in organic solvents, while also providing a protective effect against hydrolysis. This compound is often utilized in organic synthesis, particularly in the preparation of more complex silanes and as an intermediate in various chemical reactions. Safety precautions should be observed when handling this substance, as it may pose health risks due to its reactivity and potential toxicity. Proper storage conditions are also essential to maintain its integrity and prevent degradation.

Formula: C₈H₁₃Br

InChI: InChI=1/C8H13Br/c1-2-3-4-5-6-7-8-9/h2-5,8H2,1H3

SMILES: CCCCCC#CCBr

Synonyms:

• 2-(Chloromethyl)allyl-trimethylsilane
• 1-Bromooct-2-Yne

[2-(Chloromethyl)allyl]trimethylsilane

CAS: 18388-03-9

Formula: C₇H₁₅ClSi

Color and Shape: Liquid

Molecular weight: 162.7325

Ref: IN-DA003F0H

2-​(Chloromethyl)​allyl-​trimethylsilane

Controlled Product

CAS: 18388-03-9

Stability Moisture Sensitive
Applications 2-​(Chloromethyl)​allyl-​trimethylsilane is one of the reagents to synthesize Leucasandrolide A Macrolide (I) via Mukaiyama aldol coupling.2-​(Chloromethyl)​allyl-​trimethylsilane was used in catalytic Sakurai reaction of α,​β-​enones.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kopecky, D., et al.: J. Am. Chem. Soc., 123, 8420 (2001).Lee, P., et al.: J. Org. Chem., 66, 8646 (2001).

Formula: C₁₄H₁₄N₂O₄S

Color and Shape: Neat

Molecular weight: 306.337

Ref: TR-C371430