CAS 1839-18-5

2-Chloroadenine

Description:

2-Chloroadenine is a purine derivative and a halogenated analog of adenine, characterized by the presence of a chlorine atom at the 2-position of the adenine ring. Its molecular formula is C5H5ClN4, and it has a molecular weight of approximately 158.57 g/mol. This compound is typically a white to off-white solid and is soluble in polar solvents such as water and dimethyl sulfoxide (DMSO). 2-Chloroadenine exhibits biological activity, particularly as a nucleoside analog, and has been studied for its potential role in modulating various biochemical pathways, including those related to cell signaling and metabolism. It can act as an inhibitor of certain enzymes, making it of interest in pharmacological research. Additionally, due to its structural similarity to adenine, it can interfere with nucleic acid synthesis and function, which has implications in both therapeutic and research contexts. Safety data should be consulted for handling and usage, as with any chemical substance.

Formula: C₅H₄ClN₅

InChI: InChI=1/C5H4ClN5/c6-5-10-3(7)2-4(11-5)9-1-8-2/h1-2H,(H2,7,8,9,10,11)

InChI key: InChIKey=HBJGQJWNMZDFKL-UHFFFAOYSA-N

SMILES: NC1=C2C(=NC(Cl)=N1)N=CN2

Synonyms:

• 1H-Purin-6-amine, 2-chloro-
• 2-Chloro-1H-purin-6-amine
• 2-Chloro-6-Aminopurine
• 2-Chloro-7H-Purin-6-Amine
• 2-Chloro-9H-Purin-6-Amine
• 2-Chloroadenine(2-Cl-Ade)
• 2-Chlorophenthiazine
• 2-chloro-5H-purin-6-amine
• 6-Amino-2-chloro-7H-purine
• 6-Amino-2-chloro-9H-purine
• 6-Amino-2-chloropurine
• 9H-Purin-6-amine, 2-chloro-
• Adenine, 2-chloro-
• Chloroadenine
• NSC 7362
• Sq 22982

CLADRIBINE IMPURITY C CRS

CAS: 1839-18-5

CLADRIBINE IMPURITY C CRS

Formula: C₅H₄ClN₅

Color and Shape: Powder.

Molecular weight: 169.5718

Ref: 41-Y0000610

2-Chloroadenine (2-Chloro-7H-purin-6-amine)

CAS: 1839-18-5

Compounds containing a pyrimidine ring, whether or not hydrogenated, or piperazine ring in the structure, nesoi

Formula: C₅H₄ClN₅

Color and Shape: Off-White White Light Yellow Powder

Molecular weight: 169.01552

Ref: 45-1112208

2-Chloroadenine

CAS: 1839-18-5

Formula: C₅H₄ClN₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 169.5718

Ref: IN-DA003391

Cladribine EP Impurity C

CAS: 1839-18-5

Formula: C₅H₄ClN₅

Color and Shape: Pink Solid

Molecular weight: 169.57

Ref: 4Z-C-160006

Cladribine EP Impurity C

Controlled Product

CAS: 1839-18-5

Formula: C₅H₄ClN₅

Color and Shape: Neat

Molecular weight: 169.57

Ref: 86-MM3381.01

2-Chloroadenine

CAS: 1839-18-5

Formula: C₅H₄ClN₅

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow to Dark green powder to crystal

Molecular weight: 169.57

Ref: 3B-C2575

6-Amino-2-chloro-7H-purine

CAS: 1839-18-5

6-Amino-2-chloro-7H-purine

Formula: C₅H₄ClN₅

Purity: ≥95%

Color and Shape: Solid

Molecular weight: 169.57g/mol

Ref: 54-OR3724

6-Amino-2-chloropurine

CAS: 1839-18-5

6-Amino-2-chloropurine (6AC) is a nucleoside analogue that inhibits the synthesis of DNA, RNA, and protein by inhibiting the activity of polymerase chain reaction. It has been used to study the molecular mechanisms of pandemic influenza A virus and HIV infection. 6AC has also been shown to be effective in treating solid tumours and metastatic colorectal cancer in mice. This drug is also used as a competitive inhibitor for measuring endonuclease activity in polymerase chain reactions. 6AC binds to the enzyme's active site and prevents it from cleaving the DNA strands during replication, resulting in incomplete replication of the viral genome.

Formula: C₅H₄ClN₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 169.57 g/mol

Ref: 3D-FA08198

6-Amino-2-chloropurine

CAS: 1839-18-5

Formula: C₅H₄ClN₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 169.57

Ref: 10-F047747

2-Chloroadenine

CAS: 1839-18-5

Formula: C₅H₄ClN₅

Color and Shape: Neat

Molecular weight: 169.57

Ref: TR-C363835