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CAS 18390-00-6

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2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide

Description:
2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide, commonly referred to as TEMPOL, is a stable nitroxide radical characterized by its unique structure that includes an imidazoline ring and a phenyl group. This compound is known for its antioxidant properties, which allow it to scavenge free radicals and protect biological systems from oxidative stress. TEMPOL is soluble in both water and organic solvents, making it versatile for various applications in biochemical and pharmaceutical research. It exhibits a relatively stable radical character, which contributes to its effectiveness in redox reactions. Additionally, TEMPOL has been studied for its potential therapeutic effects, including its role in reducing inflammation and protecting against ischemic damage. Its stability and reactivity make it a valuable tool in studies involving oxidative stress, cellular signaling, and as a spin label in electron paramagnetic resonance (EPR) spectroscopy. Overall, TEMPOL is a significant compound in both research and potential clinical applications due to its unique chemical properties and biological activities.
Formula:C13H17N2O2
InChI:InChI=1S/C13H17N2O2/c1-12(2)13(3,4)15(17)11(14(12)16)10-8-6-5-7-9-10/h5-9H,1-4H3
InChI key:InChIKey=DYUUGILMVYJEHY-UHFFFAOYSA-N
SMILES:CC1(C)C(C)(C)N(C(=N1=O)c1ccccc1)O
Synonyms:
  • (4,4,5,5-tetramethyl-3-oxido-2-phenyl-4,5-dihydro-1H-imidazol-1-yl)oxidanyl
  • 1H-Imidazol-1-yloxy, 4,5-dihydro-4,4,5,5-tetramethyl-2-phenyl-, 3-oxide
  • 2-Imidazolin-1-yloxy, 4,4,5,5-tetramethyl-2-phenyl-, 3-oxide
  • 2-Phenyl-4,4,5,5-Tetramethylimidazoline-1-Oxyl-3-Oxide
  • 2-Phenyl-4,4,5,5-Tetramethylimidazoline-3-Oxide-1-Oxyl
  • 2-Phenyl-4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazolyl-1-oxy 3-oxide
  • 2-Phenyl-4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazolyl-1-oxyl 3-N-oxide
  • 2-Phenyl-4,4,5,5-tetramethylimidazoline-3-oxide-1-oxyl)[stablefreeradicalreagentforthesimultaneousdetermin
  • 4,4,5,5-tetramethyl-2-phenyl-4,5-dihydro-1H-imidazol-1-ol 3-oxide
  • 4,5-Dihydro-4,4,5,5-Tetramethyl-2-Phenyl-1H-Imidazol-1-Yloxy-1-Oxide
  • See more synonyms
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