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CAS 184025-18-1

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Ciproxifan

Description:
Ciproxifan is a chemical compound classified as a selective antagonist of the histamine H3 receptor, which plays a significant role in the regulation of neurotransmitter release in the central nervous system. Its chemical structure features a piperidine ring, contributing to its pharmacological properties. Ciproxifan has been studied for its potential applications in treating various neurological disorders, including cognitive impairments and sleep disorders, due to its ability to enhance the release of histamine and other neurotransmitters. The compound exhibits moderate lipophilicity, which aids in its ability to cross the blood-brain barrier, making it relevant for central nervous system activity. Additionally, Ciproxifan has been investigated for its effects on wakefulness and attention, highlighting its potential as a cognitive enhancer. However, like many pharmacological agents, its use may be accompanied by side effects, necessitating further research to fully understand its therapeutic profile and safety. Overall, Ciproxifan represents a significant interest in the field of neuropharmacology, particularly concerning histamine receptor modulation.
Formula:C16H18N2O2
InChI:InChI=1S/C16H18N2O2/c19-16(12-3-4-12)13-5-7-15(8-6-13)20-9-1-2-14-10-17-11-18-14/h5-8,10-12H,1-4,9H2,(H,17,18)
InChI key:InChIKey=ACQBHJXEAYTHCY-UHFFFAOYSA-N
SMILES:C(=O)(C1CC1)C2=CC=C(OCCCC3=CN=CN3)C=C2
Synonyms:
  • Ciproxifan
  • Fub-359
  • Methanone, cyclopropyl[4-[3-(1H-imidazol-4-yl)propoxy]phenyl]-
  • Methanone, cyclopropyl[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]-
  • cyclopropyl{4-[3-(1H-imidazol-5-yl)propoxy]phenyl}methanone
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