CAS 184025-19-2

CIPROXIFAN

Description:

Ciprofloxacin, identified by the CAS number 184025-19-2, is a synthetic fluoroquinolone antibiotic known for its broad-spectrum antibacterial activity. It primarily targets bacterial DNA gyrase and topoisomerase IV, inhibiting DNA replication and transcription, which ultimately leads to bacterial cell death. Ciprofloxacin is effective against a variety of Gram-negative and some Gram-positive bacteria, making it useful in treating infections such as urinary tract infections, respiratory tract infections, and skin infections. The compound is characterized by its relatively high solubility in water and its stability under various pH conditions. It is typically administered orally or intravenously, and its pharmacokinetics include good absorption and distribution in body tissues. However, it is essential to note that ciprofloxacin may have side effects, including gastrointestinal disturbances and potential effects on tendons, particularly in older adults. As with all antibiotics, appropriate use is crucial to prevent the development of antibiotic resistance.

Formula: C₂₀H₂₂N₂O₆

InChI: InChI=1/C16H18N2O2.C4H4O4/c19-16(12-3-4-12)13-5-7-15(8-6-13)20-9-1-2-14-10-17-11-18-14;5-3(6)1-2-4(7)8/h5-8,10-12H,1-4,9H2,(H,17,18);1-2H,(H,5,6)(H,7,8)/b;2-1-

SMILES: C(Cc1cnc[nH]1)COc1ccc(cc1)C(=O)C1CC1.C(=C\C(=O)O)\C(=O)O

Synonyms:

• FUB 359 maleate salt, Cyclopropyl (4-[3-(1H-imidazol-4-yl)propyloxy]phenyl) ketone maleate salt
• cyclopropyl{4-[3-(1H-imidazol-5-yl)propoxy]phenyl}methanone (2Z)-but-2-enedioate

Ciproxifan maleate(FUB-359 maleate)

CAS: 184025-19-2

Formula: C₂₀H₂₂N₂O₆

Purity: 95%

Color and Shape: Solid

Molecular weight: 386.3985

Ref: IN-DA003OX2

Ciproxifan maleate

CAS: 184025-19-2

Formula: C₁₆H₁₈N₂O₂·C₄H₄O₄

Molecular weight: 386.40

Ref: 7W-GP7554

Ciproxifan maleate

CAS: 184025-19-2

Ciproxifan maleate

Purity: ≥98%

Molecular weight: 386.4g/mol

Ref: 54-BUP02625

Ciproxifan maleate

CAS: 184025-19-2

Ciproxifan maleate (FUB 359)(FUB-359 maleate) is a highly potent and selective histamin H3-receptor antagonist with IC50 of 9.2 nM, with low apparent affinity

Formula: C₂₀H₂₂N₂O₆

Purity: 99.39%

Color and Shape: Solid

Molecular weight: 386.4

Ref: TM-T2004

Ciproxifan maleate

CAS: 184025-19-2

Inverse agonist/antagonist of H3 histamine receptor

Formula: C₂₀H₂₂N₂O₆

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 386.4 g/mol

Ref: 3D-FC64979

Ciproxifan Maleate

Controlled Product

CAS: 184025-19-2

Applications Ciproxifan is a potent histamine H3 receptor antagonist which affects histamine levels in the brain. It may be used in treatments for sleep and neurological disorders.
References Stark, H. et al.: J. Med. Chem., 43, 3987 (2000); Mahmood, D. et al.: Pharmacolol. Rep., 64, 191 (2012); Passani, M. et al.: Trends Pharmacol. Sci., 25, 618 (2004);

Formula: C₁₆H₁₈N₂O₂·C₄H₄O₄

Color and Shape: Neat

Molecular weight: 386.40

Ref: TR-C484000