CAS 18422-43-0

5'-Cytidylic acid, 2'-O-methyl-

Description:

5'-Cytidylic acid, 2'-O-methyl- is a modified nucleotide that plays a significant role in molecular biology and biochemistry. It is a derivative of cytidine monophosphate (CMP), where a methyl group is added to the 2' hydroxyl group of the ribose sugar, enhancing its stability and resistance to enzymatic degradation. This modification can influence the molecule's interactions with other nucleic acids and proteins, making it useful in various applications, including RNA synthesis and therapeutic development. The presence of the 5' phosphate group is crucial for its incorporation into RNA strands during transcription. Additionally, the methylation at the 2' position can affect the secondary structure and function of RNA, potentially impacting gene expression and regulation. Due to these characteristics, 5'-Cytidylic acid, 2'-O-methyl- is often utilized in research and therapeutic contexts, particularly in the design of RNA-based drugs and in the study of RNA biology.

Formula: C₁₀H₁₆N₃O₈P

2'-O-Methylcytidine-5'-monophosphate triethylammonium salt

CAS: 18422-43-0

2'-O-Methylcytidine-5'-monophosphate triethylammonium salt is a synthetic nucleoside that has been shown to be a substrate for DNA polymerase and an inhibitor of RNA synthesis. It has been used in the laboratory as a primer and as a biochemical tool to study viruses. 2'-O-Methylcytidine-5'-monophosphate triethylammonium salt is active against murine leukemia virus, but not against ciliated protozoan parasites such as Tetrahymena pyriformis. This compound has also been shown to inhibit the enzyme form of HIV reverse transcriptase and to be cytotoxic at high concentrations.

Formula: C₁₀H₁₆N₃O₈P•C₆H₁₅N

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 438.41 g/mol

Ref: 3D-NM167711