CAS 18423-43-3

thymidine 5'-triphosphate

Description:

Thymidine 5'-triphosphate (dTTP) is a nucleotide that plays a crucial role in cellular metabolism and DNA synthesis. It is composed of a thymine base, a deoxyribose sugar, and three phosphate groups. As a building block of DNA, dTTP is essential for the polymerization of nucleotides during DNA replication and repair processes. The triphosphate structure provides high-energy bonds, which are utilized during the formation of DNA strands. dTTP is also involved in various biochemical pathways, including those related to energy transfer and signaling. In terms of solubility, dTTP is typically soluble in water, making it accessible for enzymatic reactions in biological systems. Its stability can be influenced by pH and temperature, and it is sensitive to hydrolysis, which can lead to the breakdown of the nucleotide. Overall, thymidine 5'-triphosphate is a vital component in molecular biology, particularly in studies involving DNA synthesis and manipulation.

Formula: C₁₀H₁₇N₂O₁₄P₃

InChI: InChI=1/C10H17N2O14P3.Na/c1-5-3-12(10(15)11-9(5)14)8-2-6(13)7(24-8)4-23-28(19,20)26-29(21,22)25-27(16,17)18;/h3,6-8,13H,2,4H2,1H3,(H,19,20)(H,21,22)(H,11,14,15)(H2,16,17,18);

SMILES: Cc1cn(C2CC(C(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)O)c(=O)nc1O.[Na]

Synonyms:

• dTTP
• 2-Deoxythymidine-5-triphosphate
• Thymidine-5-triphosphoric acid
• Thiazolium, 3-[(4-Amino-2-Methyl-5-Pyrimidinyl)Methyl]-5-[2-[[Hydroxy[[Hydroxy(Phosphonooxy)Phosphinyl]Oxy]Phosphinyl]Oxy]Ethyl]-4-Methyl-, Inner Salt
• 1,1'-Binaphthalene-2,2'-Diamine
• 2,4(1H,3H)-pyrimidinedione, 1-[2-deoxy-5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]pentofuranosyl]-5-methyl-
• Deoxythymidine triphosphate
• 2'-Deoxythymidine triphosphate
• 5'-Ttp
• Deoxy-TTP
• Deoxythymidine 5'-triphosphate
• TTP (nucleotide)
• Thymidine 5'-(tetrahydrogen triphosphate)
• 1-[2-deoxy-5-O-(hydroxy{[hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl)pentofuranosyl]-5-methylpyrimidine-2,4(1H,3H)-dione

Thymidine 5'-(tetrahydrogen triphosphate) sodium salt

CAS: 18423-43-3

Formula: C₁₀H₁₇N₂NaO₁₄P₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 505.1580

Ref: IN-DA00I1GR

2'-Deoxythymidine-5'-Triphosphate Sodium Salt

CAS: 18423-43-3

2'-Deoxythymidine-5'-Triphosphate Sodium Salt

Purity: 97%

Molecular weight: 482.17g/mol

Ref: 54-OR1024139

Deoxythymidine triphosphate

CAS: 18423-43-3

Deoxythymidine triphosphate

Purity: ≥95%

Molecular weight: 548.11g/mol

Ref: 54-BUP05081

2''-Deoxythymidine 5''-triphosphate trisodium salt (dTTP); 100mM solution

CAS: 18423-43-3

Formula: C₁₀H₁₄N₂Na₃O₁₄P₃

Purity: ≥ 99.0% (triphosphate content)

Color and Shape: Clear, colourless liquid

Molecular weight: 548.11

Ref: 7W-GE2816

Thymidine 5''-triphosphate sodium salt

CAS: 18423-43-3

Molecular weight: 504.15

Ref: 7W-GV4060

Deoxythymidine triphosphate

CAS: 18423-43-3

Deoxythymidine triphosphate (dTTP) is one of the four nucleoside triphosphates that are used in the in vivo synthesis of DNA.

Formula: C₁₀H₁₄N₂Na₃O₁₄P₃

Purity: 99.78%

Color and Shape: White Amorphous Powder

Molecular weight: 548.11

Ref: TM-T1663

Thymidine 5’-Triphosphate Sodium Hydrate (>85%)

Controlled Product

CAS: 18423-43-3

Applications A metabolite of Thymidine (T412000). Also, a Thymidine (T412000) analogue as phosphate donor.
References Lyu, B., et al.: Anal. Biochem., 220, 410 (1994),

Formula: C₁₀H₁₇N₂O₁₄P₃·xNa·xH₂O

Color and Shape: Neat

Molecular weight: 526.13

Ref: TR-T410010

Deoxythymidine Triphosphate Trisodium Salt (dTTP), 98%

CAS: 18423-43-3

Formula: C₁₀H₁₄N₂O₁₄P₃Na₃

Purity: min. 98%

Color and Shape: White, Powder

Molecular weight: 548.10

Ref: SR-42197

Thymidine-5'-triphosphate sodium salt - 100mM aqueous solution

CAS: 18423-43-3

Thymidine-5'-triphosphate sodium salt is a modified nucleoside with anticancer properties. It is a high-quality, high-purity ribonucleoside that can be used as an activator for the synthesis of deoxyribonucleosides and phosphoramidites. Thymidine-5'-triphosphate sodium salt has antiviral activity, which is due to its ability to inhibit viral DNA replication and transcription. This compound also has the potential to be used in the treatment of cancer cells by inhibiting DNA synthesis and cell division.

Formula: C₁₀H₁₇N₂O₁₄P₃·xNa

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 482.17 g/mol

Ref: 3D-NT10135