CAS 184241-44-9

5-Chloro-N4-(cyclopropylmethyl)-2-methyl-N4-propyl-N6-(2,4,6-trichlorophenyl)-4,6-pyrimidinediamine

Description:

5-Chloro-N4-(cyclopropylmethyl)-2-methyl-N4-propyl-N6-(2,4,6-trichlorophenyl)-4,6-pyrimidinediamine, with CAS number 184241-44-9, is a synthetic organic compound characterized by its complex structure, which includes a pyrimidine core substituted with various functional groups. This compound features a chloro substituent, cyclopropylmethyl and propyl side chains, and a trichlorophenyl group, contributing to its potential biological activity. The presence of multiple chlorine atoms suggests that it may exhibit unique chemical properties, such as increased lipophilicity and potential interactions with biological targets. Its structure indicates that it may be of interest in medicinal chemistry, particularly in the development of pharmaceuticals targeting specific pathways or diseases. The compound's solubility, stability, and reactivity would depend on the specific conditions and solvents used, and its biological activity would require further investigation through in vitro and in vivo studies. Overall, this compound exemplifies the complexity often found in drug design and development.

Formula: C₁₈H₂₀Cl₄N₄

InChI: InChI=1/C18H20Cl4N4/c1-3-6-26(9-11-4-5-11)18-15(22)17(23-10(2)24-18)25-16-13(20)7-12(19)8-14(16)21/h7-8,11H,3-6,9H2,1-2H3,(H,23,24,25)

InChI key: InChIKey=KNADXBVKFAUMCR-UHFFFAOYSA-N

SMILES: N(CC1CC1)(CCC)C=2C(Cl)=C(NC3=C(Cl)C=C(Cl)C=C3Cl)N=C(C)N2

Synonyms:

• 4,6-Pyrimidinediamine, 5-chloro-N-(cyclopropylmethyl)-2-methyl-N-propyl-N′-(2,4,6-trichlorophenyl)-
• 4,6-Pyrimidinediamine, 5-chloro-N⁴-(cyclopropylmethyl)-2-methyl-N⁴-propyl-N⁶-(2,4,6-trichlorophenyl)-
• 5-Chloro-N-(cyclopropylmethyl)-2-methyl-N-propyl-N'-(2,4,6-trichlorophenyl)-4,6-pyrimidinediaminehydrochloride
• 5-Chloro-N⁴-(cyclopropylmethyl)-2-methyl-N⁴-propyl-N⁶-(2,4,6-trichlorophenyl)-4,6-pyrimidinediamine
• 5-chloro-N-(cyclopropylmethyl)-2-methyl-N-propyl-N'-(2,4,6-trichlorophenyl)pyrimidine-4,6-diamine
• NBI27914HCl
• Nbi 27914
• Nbi 27914 Hydrochloride
• 5-Chloro-N4-(cyclopropylmethyl)-2-methyl-N4-propyl-N6-(2,4,6-trichlorophenyl)-4,6-pyrimidinediamine
• 4,6-Pyrimidinediamine, 5-chloro-N4-(cyclopropylmethyl)-2-methyl-N4-propyl-N6-(2,4,6-trichlorophenyl)-
• 5-CHLORO-N-(CYCLOPROPYLMETHYL)-2-METHYL-N-PROPYL-N'-(2,4,6-TRICHLOROPHENYL)-4,6-PYRIMIDINEDIAMINE HYDROCHLORIDE
• NBI 27914 >=98% (HPLC)

NBI-27914

CAS: 184241-44-9

NBI-27914

Purity: ≥98%

Ref: 54-BUP22716

NBI 27914

CAS: 184241-44-9

Formula: C₁₈H₂₀Cl₄N₄

Molecular weight: 434.19

Ref: 7W-GK1173

NBI-27914

CAS: 184241-44-9

NBI-27914 is a selective and non-peptide CRFR1 (corticotropin-releasing factor receptor 1) antagonist with analgesic effects, capable of blocking CRF-induced anxiety.

Formula: C₁₈H₂₀Cl₄N₄

Purity: 99.47% - 99.64%

Color and Shape: Solid

Molecular weight: 434.19

Ref: TM-T62444