CAS 18444-66-1: Cucurbitacin E

Description:Cucurbitacin E is a triterpenoid compound primarily derived from various plants in the Cucurbitaceae family, such as cucumbers and gourds. It is known for its bitter taste and has been studied for its potential pharmacological properties, including anti-cancer, anti-inflammatory, and anti-diabetic effects. The molecular structure of Cucurbitacin E features a tetracyclic framework, which is characteristic of cucurbitacins, contributing to its biological activity. This compound exhibits a range of biological activities, including the ability to inhibit cell proliferation and induce apoptosis in certain cancer cell lines. Additionally, Cucurbitacin E has been investigated for its effects on various signaling pathways, such as the NF-κB and MAPK pathways, which are crucial in inflammation and cancer progression. Due to its potent biological effects, Cucurbitacin E is of interest in medicinal chemistry and natural product research, although its bitter taste and potential toxicity at high doses necessitate careful consideration in therapeutic applications.

Formula:C₃₂H₄₄O₈

InChI:InChI=1S/C32H44O8/c1-17(33)40-27(2,3)13-12-23(36)32(9,39)25-21(35)15-29(6)22-11-10-18-19(14-20(34)26(38)28(18,4)5)31(22,8)24(37)16-30(25,29)7/h10,12-14,19,21-22,25,34-35,39H,11,15-16H2,1-9H3/b13-12+/t19-,21-,22+,25+,29+,30-,31+,32+/m1/s1

InChI key:InChIKey=NDYMQXYDSVBNLL-MUYMLXPFSA-N

SMILES:O=C(OC(C=CC(=O)C(O)(C)C1C(O)CC2(C)C3CC=C4C(C=C(O)C(=O)C4(C)C)C3(C(=O)CC12C)C)(C)C)C

Synonyms:
(23E)-2,16,20-trihydroxy-9,10,14-trimethyl-1,11,22-trioxo-4,9-cyclo-9,10-secocholesta-2,5,23-trien-25-yl acetate
(4R,9beta,16alpha,23E)-2,16,20-trihydroxy-9,10,14-trimethyl-1,11,22-trioxo-4,9-cyclo-9,10-secocholesta-2,5,23-trien-25-yl acetate
(9β,10α,16α,23E)-25-(Acetyloxy)-2,16,20-trihydroxy-9-methyl-19-norlanosta-1,5,23-triene-3,11,22-trione
18444-66-1
19-Nor-9β,10α-lanosta-1,5,23-triene-3,11,22-trione, 2,16α,20,25-tetrahydroxy-9-methyl-, 25-acetate
19-Norlanosta-1,5,23-triene-3,11,22-trione, 25-(acetyloxy)-2,16,20-trihydroxy-9-methyl-, (9β,10α,16α,23E)-
2,16,20-Trihydroxy-9,10,14-Trimethyl-1,11,22-Trioxo-4,9-Cyclo-9,10-Secocholesta-2,5,23-Trien-25-Yl Acetate
Cucurbitacine E
NSC 106399
NSC 521775
See more synonyms
[(E)-5-[(8S,9R,10R,13R,14S,16R,17R)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-8,10,12,15,16,17-hexahydro-7H-cyclopenta[a]phenanthren-17-yl]-5-hydroxy-1,1-dimethyl-4-oxo-hex-2-enyl] acetate
cucurbitacin E
α-Elaterin
α-Elaterine

Found 10 products.

Product data	Purity	Price range	Estimated delivery
Cucurbitacin E REF: 11-0020SCAS: 18444-66-1	(HPLC) ≥95%	125.00 €	Thu 10 Apr 25
19-Norlanosta-1,5,23-triene-3,11,22-trione,25-(acetyloxy)-2,16,20-trihydroxy-9-methyl-, (9b,10a,16a,23E)- REF: IN-DA00I1GWCAS: 18444-66-1	%	57.00 €~562.00 €	Tue 15 Apr 25
Cucurbitacin E REF: 54-BUP04604CAS: 18444-66-1	99.19%	457.00 €~944.00 €	Wed 16 Apr 25
Cucurbitacin E REF: BP-BP0416CAS: 18444-66-1	95%~99%	222.00 €~1,016.00 €	Mon 21 Apr 25
Cucurbitacin E REF: TM-T5S1467CAS: 18444-66-1	98.88% - 99.19%	59.00 €~643.00 €	Tue 22 Apr 25
Cucurbitacin E REF: 4Z-C-266001CAS: 18444-66-1	- - -	To inquire	Tue 22 Apr 25
Cucurbitacin E REF: 7W-GY1460CAS: 18444-66-1	≥ 98.0%	101.00 €~740.00 €	Tue 22 Apr 25
Cucurbitacin e REF: 5G-80013CAS: 18444-66-1	≥ 95.0 % (HPLC)	185.00 €~12,573.00 €	Thu 24 Apr 25
Cucurbitacin E REF: 3D-FC69737CAS: 18444-66-1	Min. 95%	143.00 €~2,224.00 €	Mon 28 Apr 25
Cucurbitacin E REF: TR-C838800CAS: 18444-66-1	- - -	343.00 €~2,314.00 €	Tue 06 May 25