CAS 1844874-26-5

D-arabino-Hexitol, 5-amino-2,6-anhydro-1,3,4,5-tetradeoxy-6-C-(2,5-difluorophenyl)-3-[2,6-dihydro-2-(methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(4H)-yl]-1,1,1-trifluoro-, (6R)-

Description:

D-arabino-Hexitol, 5-amino-2,6-anhydro-1,3,4,5-tetradeoxy-6-C-(2,5-difluorophenyl)-3-[2,6-dihydro-2-(methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(4H)-yl]-1,1,1-trifluoro-, (6R)- is a complex organic compound characterized by its unique structural features, including multiple functional groups and stereochemistry. This substance contains a hexitol backbone, which is a sugar alcohol, and incorporates an anhydro sugar moiety, indicating a dehydration reaction that enhances its stability and reactivity. The presence of amino and trifluoromethyl groups suggests potential biological activity, possibly influencing its interaction with biological targets. Additionally, the difluorophenyl and methylsulfonyl substituents may contribute to its lipophilicity and solubility properties, making it suitable for various applications in medicinal chemistry. The specific stereochemistry (6R) indicates the spatial arrangement of atoms, which is crucial for its biological function and activity. Overall, this compound's intricate structure and functional diversity position it as a candidate for further research in pharmaceutical development and chemical synthesis.

Formula: C₁₈H₁₉F₅N₄O₃S

Synonyms:

• Compound COFROGLIPTIN
• cofrogliptin
• D-arabino-Hexitol, 5-amino-2,6-anhydro-1,3,4,5-tetradeoxy-6-C-(2,5-difluorophenyl)-3-[2,6-dihydro-2-(methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(4H)-yl]-1,1,1-trifluoro-, (6R)-

Cofrogliptin

CAS: 1844874-26-5

Cofrogliptin (HSK7653) is a DPP-4 inhibitor with hypoglycemic effects, which can be used to study type 2 diabetes (T2D).

Formula: C₁₈H₁₉F₅N₄O₃S

Color and Shape: Solid

Molecular weight: 466.43

Ref: TM-T62985