CAS 1845-11-0

Nafoxidine

Description:

Nafoxidine is a synthetic compound classified as a non-steroidal antiestrogen, primarily known for its application in research related to breast cancer treatment. It functions by binding to estrogen receptors, thereby inhibiting the effects of estrogen in tissues where it may promote tumor growth. Nafoxidine is characterized by its chemical structure, which includes a phenolic group and a side chain that contributes to its biological activity. The compound is typically administered in a laboratory setting for experimental purposes rather than as a standard therapeutic agent. Its pharmacological profile includes potential effects on various biological pathways, making it a subject of interest in studies exploring hormone-dependent cancers. Nafoxidine's safety and efficacy profiles are still under investigation, and it is important to handle it with care in laboratory environments due to its biological activity. As with many chemical substances, proper safety protocols should be followed when working with Nafoxidine to mitigate any potential risks associated with its use.

Formula: C₂₉H₃₁NO₂

InChI: InChI=1S/C29H31NO2/c1-31-26-14-16-28-24(21-26)11-15-27(22-7-3-2-4-8-22)29(28)23-9-12-25(13-10-23)32-20-19-30-17-5-6-18-30/h2-4,7-10,12-14,16,21H,5-6,11,15,17-20H2,1H3

InChI key: InChIKey=JEYWNNAZDLFBFF-UHFFFAOYSA-N

SMILES: O(C)C=1C=C2C(C(=C(CC2)C3=CC=CC=C3)C4=CC=C(OCCN5CCCC5)C=C4)=CC1

Synonyms:

• 1-(2-(p-(3,4-Dihydro-6-methoxy-2-phenyl-1-naphthyl)phenoxy)ethyl)pyrrolidine
• 1-[2-[4-(3,4-Dihydro-6-methoxy-2-phenyl-1-naphthalenyl)phenoxy]ethyl]pyrrolidine
• 1-[2-[4-(6-Methoxy-2-phenyl-3,4-dihydronaphthalen-1-yl)phenoxy]ethyl]pyrrolidine
• Brn 1440873
• Nafoxidene
• Nafoxidina
• Nafoxidina [INN-Spanish]
• Nafoxidine [INN]
• Nafoxidinum
• Nafoxidinum [INN-Latin]
• Nsc 70735
• Pyrrolidine, 1-(2-(4-(3,4-dihydro-6-methoxy-2-phenyl-1-naphthalenyl)phenoxy)ethyl)-
• Pyrrolidine, 1-(2-(p-(3,4-dihydro-6-methoxy-2-phenyl-1-naphthyl)phenoxy)ethyl)-
• Nafoxidine
• 5-20-01-00210 (Beilstein Handbook Reference)

Nafoxidine

CAS: 1845-11-0

Nafoxidine

Purity: ≥98%

Molecular weight: 425.56g/mol

Ref: 54-BUP05758

Nafoxidine

CAS: 1845-11-0

Nafoxidine is an estrogen antagonist that has been used in the treatment of breast cancer.

Formula: C₂₉H₃₁NO₂

Purity: 99.93%

Color and Shape: Solid

Molecular weight: 425.56

Ref: TM-T21387L

1-[2-[4-(6-Methoxy-2-phenyl-3,4-dihydronaphthalen-1-yl)phenoxy]ethyl]pyrrolidine

CAS: 1845-11-0

1-[2-[4-(6-Methoxy-2-phenyl-3,4-dihydronaphthalen-1-yl)phenoxy]ethyl]pyrrolidine (EMDNP) is a ligand that binds to the ion channels TRPV1 and TRPA1. It has been used as a research tool for protein interactions, pharmacology, and cell biology. EMDPN is a high purity compound with an inhibitor activity.
EMDNP has been shown to be an activator of TRPV1 channels. This activation leads to the release of substance P and calcitonin gene related peptide from sensory neurons which results in pain relief.

Formula: C₂₉H₃₁NO₂

Purity: Min. 95%

Molecular weight: 425.6 g/mol

Ref: 3D-BAA84511