CAS 18464-39-6

Caroxazone

Description:

Caroxazone is a chemical compound classified as an antidepressant and belongs to the class of drugs known as monoamine oxidase inhibitors (MAOIs). It is primarily used in the treatment of depressive disorders. The molecular structure of caroxazone features a phenyl ring and a hydrazone functional group, contributing to its pharmacological activity. The compound is known for its ability to inhibit the enzyme monoamine oxidase, which plays a crucial role in the metabolism of neurotransmitters such as serotonin, norepinephrine, and dopamine. By inhibiting this enzyme, caroxazone can increase the levels of these neurotransmitters in the brain, potentially alleviating symptoms of depression. Caroxazone is typically administered orally and may have side effects, including dizziness, dry mouth, and gastrointestinal disturbances. As with other MAOIs, it is essential for patients to avoid certain foods and medications that can lead to hypertensive crises due to interactions. Overall, caroxazone represents a significant option in the pharmacotherapy of depression, although its use may be limited by dietary restrictions and side effects.

Formula: C₁₀H₁₀N₂O₃

InChI: InChI=1S/C10H10N2O3/c11-9(13)6-12-5-7-3-1-2-4-8(7)15-10(12)14/h1-4H,5-6H2,(H2,11,13)

InChI key: InChIKey=KYCBWEZLKCTALM-UHFFFAOYSA-N

SMILES: C(C(N)=O)N1CC=2C(OC1=O)=CC=CC2

Synonyms:

• 18464-39-6
• 2-(2-Oxo-3,4-dihydro-2H-1,3-benzoxazin-3-yl)acetamide
• 2-(2-Oxo-4H-1,3-benzoxazin-3-yl)acetamide
• 2-(2-oxo-2H-1,3-benzoxazin-3(4H)-yl)acetamide
• 2-Oxo-2H-1,3-benzoxazine-3(4H)-acetamide
• 242-345-1
• 2H-1,3-Benzoxazine-3(4H)-acetamide, 2-oxo-
• 4H-3-(Carbamoylmethyl)-1,3-benzoxazin-2-one
• Fi 6654
• Timostenil
• Caroxazone

Caroxazone

Controlled Product

CAS: 18464-39-6

Applications Caroxazone acts as an irreversible, nonselective MAO inhibitor, displaying antidepressant characteristics.
References Moretti, A. et al.: Br. J. Clin. Pharmacol., 11, 511 (1981); De Angelis, L. et al.: Drugs of Today., 12, 235 (1976);

Formula: C₁₀H₁₀N₂O₃

Color and Shape: Neat

Molecular weight: 206.198

Ref: TR-C184260

2,3-Dihydro-4H-1,3-benzoxazin-2-one-3-acetamide

Controlled Product

CAS: 18464-39-6

2,3-Dihydro-4H-1,3-benzoxazin-2-one-3-acetamide is a high purity and potent competitive antagonist of the nicotinic acetylcholine receptor (nAChR) that binds to the extracellular domain of the α7 subtype. It can be used as a research tool in pharmacology and cell biology to study ligand binding interactions with nAChRs. It has been shown to inhibit the binding of acetylcholine in rat brain synaptosomes. 2,3-Dihydro-4H-1,3-benzoxazin-2-one-3-acetamide is also an inhibitor of protein synthesis and has been shown to bind to the peptide chain elongation factor 2 (EF2) by inhibiting its activity.

Formula: C₁₀H₁₀N₂O₃

Purity: Min. 95%

Molecular weight: 206.2 g/mol

Ref: 3D-TAA46439

Caroxazone

CAS: 18464-39-6

Caroxazone is an antidepressant drug, monoamine oxidase inhibitor (MAOI) that is irreversible and nonselective meanwhile.

Formula: C₁₀H₁₀N₂O₃

Color and Shape: Solid

Molecular weight: 206.2

Ref: TM-T25205