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CAS 18472-51-0

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Chlorhexidine gluconate

Description:
Chlorhexidine gluconate is a broad-spectrum antiseptic and disinfectant commonly used in medical and dental settings. It is a cationic bisbiguanide compound, characterized by its ability to disrupt microbial cell membranes, leading to cell death. This substance is effective against a wide range of bacteria, fungi, and some viruses, making it a popular choice for skin disinfection, surgical scrubs, and oral rinses. Chlorhexidine gluconate is typically available in various formulations, including solutions, gels, and impregnated dressings. It is known for its residual antimicrobial activity, which allows it to remain effective on the skin or mucous membranes for an extended period after application. While generally well-tolerated, it can cause skin irritation or allergic reactions in some individuals. Additionally, its use is contraindicated in certain situations, such as in patients with a known hypersensitivity to chlorhexidine or in specific surgical procedures involving the ear or meninges. Overall, chlorhexidine gluconate is a valuable tool in infection control and hygiene practices.
Formula:C34H54Cl2N10O14
InChI:InChI=1/C22H30Cl2N10.2C6H12O7/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18;2*7-1-2(8)3(9)4(10)5(11)6(12)13/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34);2*2-5,7-11H,1H2,(H,12,13)
InChI key:InChIKey=KUXUALPOSMRJSW-IFWQJVLJSA-N
SMILES:[C@H]([C@@H]([C@@H](CO)O)O)([C@H](C(O)=O)O)O.N(C(NC(NCCCCCCNC(NC(NC1=CC=C(Cl)C=C1)=N)=N)=N)=N)C2=CC=C(Cl)C=C2
Synonyms:
  • 1,1'-Hexamethylenebis[5-(4-chlorophenyl)biguanide] digluconate
  • 1,1'-Hexamethylenebis[5-(p-chlorophenyl)biguanide] digluconate
  • 1,1′-Hexamethylene-bis(5-(p-chlorophenyl)biguanide)
  • 1,6-Bis(4-chlorophenyldiguanino)hexane digluconate
  • 1,6-Bis(p-chlorophenyldiguanido)hexane digluconate
  • 1,6-Bis[N5-(p-chlorophenyl)biguanido]hexane digluconate
  • 1,6-Bis[N<sup>5</sup>-(p-chlorophenyl)biguanido]hexane digluconate
  • 2,4,11,13-Tetraazatetradecanediimidamide, N,N′′-bis(4-chlorophenyl)-3,12-diimino-, di-<span class="text-smallcaps">D</span>-gluconate
  • <span class="text-smallcaps">D</span>-Gluconic acid, compd. with 1,1′-hexamethylenebis[5-(p-chlorophenyl)biguanide] (2:1)
  • <span class="text-smallcaps">D</span>-Gluconic acid, compd. with N,N′′-bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide (2:1)
  • See more synonyms
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Found 12 products.