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CAS 184763-07-3

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1-Fmoc-2-azetidinecarboxylic acid

Description:
1-Fmoc-2-azetidinecarboxylic acid is a chemical compound characterized by its unique structure, which includes an azetidine ring and a Fmoc (9-fluorenylmethoxycarbonyl) protecting group. This compound is primarily used in organic synthesis and peptide chemistry, particularly for the protection of amino acids during peptide synthesis. The presence of the azetidine ring contributes to its rigidity and can influence the conformation of peptides, potentially affecting their biological activity. The Fmoc group is widely utilized for its ease of removal under mild basic conditions, making it a popular choice in solid-phase peptide synthesis. Additionally, 1-Fmoc-2-azetidinecarboxylic acid exhibits properties typical of carboxylic acids, such as the ability to form hydrogen bonds and participate in acid-base reactions. Its specific reactivity and stability can be influenced by the surrounding chemical environment, making it a valuable intermediate in the development of pharmaceuticals and biologically active compounds. Overall, this compound serves as an important tool in the field of medicinal chemistry and peptide design.
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