CAS 184763-26-6

21(R)-Hydroxy Montelukast

Description:

21(R)-Hydroxy Montelukast is a chemical compound that serves as a metabolite of Montelukast, a leukotriene receptor antagonist primarily used in the management of asthma and allergic rhinitis. This compound is characterized by its specific stereochemistry, indicated by the (R) configuration at the 21st carbon position, which influences its biological activity and interaction with leukotriene receptors. The molecular structure includes a carboxylic acid functional group, contributing to its solubility and reactivity. As a derivative of Montelukast, 21(R)-Hydroxy Montelukast retains similar pharmacological properties, potentially offering insights into the drug's metabolism and efficacy. The compound's CAS number, 184763-26-6, allows for precise identification in chemical databases and literature. Its characteristics, including molecular weight, solubility, and stability, are essential for understanding its role in pharmacokinetics and pharmacodynamics. Overall, 21(R)-Hydroxy Montelukast represents an important aspect of research into the therapeutic mechanisms of leukotriene antagonists.

Formula: C₃₅H₃₆ClNO₄S

InChI: InChI=1/C35H36ClNO4S/c1-34(2,41)29-9-4-3-8-28(29)31(38)20-32(42-22-35(16-17-35)21-33(39)40)25-7-5-6-23(18-25)10-14-27-15-12-24-11-13-26(36)19-30(24)37-27/h3-15,18-19,31-32,38,41H,16-17,20-22H2,1-2H3,(H,39,40)/b14-10+/t31-,32+/m0/s1

Synonyms:

• [R-[R*,R*-(E)]]-1-[[[1-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxy-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]-cyclopropaneacetic Aci
• [R-[R*,R*-(E)]]-1-[[[1-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxy-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]-cyclopropaneacetic Acid
• {1-[({(1R,3S)-1-{3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-hydroxy-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl}sulfanyl)methyl]cyclopropyl}acetic acid

21(R)-Hydroxy Montelukast-d6

Controlled Product

CAS: 184763-26-6

Formula: C₃₅D₆H₃₀ClNO₄S

Color and Shape: Neat

Molecular weight: 608.22

Ref: TR-H948462

21(R)-Hydroxy Montelukast

CAS: 184763-26-6

Formula: C₃₅H₃₆ClNO₄S

Molecular weight: 602.19

Ref: ST-EA-CP-M25027