CAS 1849590-01-7

eFT-508

CAS: 1849590-01-7

Formula: C₁₇H₂₀N₆O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 340.3797

Ref: IN-DA00ABRG

Tomivosertib

CAS: 1849590-01-7

Tomivosertib

Purity: ≥95%

Molecular weight: 340.38g/mol

Ref: 54-BUP07402

eFT508

CAS: 1849590-01-7

eFT508

Formula: C₁₇H₂₀N₆O₂

Purity: 98.8% (Typical Value in Batch COA)

Color and Shape: pale yellow solid

Molecular weight: 340.38g/mol

Ref: 54-BISN0203

Tomivosertib

CAS: 1849590-01-7

Tomivosertib (eFT508) is a potent, highly selective MNK1 and MNK2 inhibitor with IC50 value of 1-2 nM.

Formula: C₁₇H₂₀N₆O₂

Purity: 97.34% - 99.72%

Color and Shape: Solid

Molecular weight: 340.38

Ref: TM-T3468

6'-[(6-Amino-4-pyrimidinyl)amino]-8'-methylspiro[cyclohexane-1,3'(2'H)-imidazo[1,5-a]pyridine]-1',5'-dione

Controlled Product

CAS: 1849590-01-7

Applications 6'-[(6-Amino-4-pyrimidinyl)amino]-8'-methylspiro[cyclohexane-1,3'(2'H)-imidazo[1,5-a]pyridine]-1',5'-dione was used in the study of inhibitors of immune checkpoint modulators and related methods. eFT508 is a potent, highly selective, and orally bioavailable MNK1 and MNK2 inhibitor.
References Webster, K., et al.: U.S. Pat. Appl. Publ. (2016), US 20160303124 A1 20161020; Webster, K., et al.: Blood, 126, 1554 (2015);

Formula: C₁₇H₂₀N₆O₂

Color and Shape: Neat

Molecular weight: 340.38

Ref: TR-A629153

eFT 508

CAS: 1849590-01-7

Dual inhibitor of MNK1/2 (regulators of mRNA translation)

Formula: C₁₇H₂₀N₆O₂

Purity: Min. 95%

Molecular weight: 340.38 g/mol

Ref: 3D-BE168437