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CAS 185039-91-2

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Found 2 products.
  • PD166326
    Biosynth
    + Info

    PD166326

    CAS:
    <p>PD166326 is a protein data inhibitor drug that is used to inhibit the bcr-abl kinase, which is responsible for the uncontrolled proliferation of cells in cancer. PD166326 has been shown to inhibit the kinase activity of bcr-abl and increase mitochondrial membrane potential, leading to cell death by apoptosis. The compound has also been shown to inhibit the growth of skin cancer cells in mice. PD166326 binds to an active site on bcr-abl and blocks its ATP binding site, preventing phosphorylation of downstream substrates such as paxillin and caspase 3, which are involved in cell proliferation. This drug has also been shown to be effective against myelogenous leukemia cells in mice.</p>
    Formula:C21H16Cl2N4O2
    Purity:Min. 95%
    Molecular weight:427.28 g/mol

    Ref: 3D-KHA03991

    50mg
    4,317.00€
  • PD 166326
    Targetmol
    + Info

    PD 166326

    CAS:
    <p>PD166326, a pyridopyrimidine inhibitor, targets Src &amp; Abl tyrosine kinases (IC50: 6 nM &amp; 8 nM) and exhibits antileukemic effects.</p>
    Formula:C21H16Cl2N4O2
    Color and Shape:Solid
    Molecular weight:427.28

    Ref: TM-T22132