CAS 185116-43-2

4-(fmoc-amino)benzoic acid

Description:

4-(Fmoc-amino)benzoic acid, with the CAS number 185116-43-2, is an aromatic compound characterized by the presence of a benzoic acid moiety substituted with a 9-fluorenylmethoxycarbonyl (Fmoc) group at the para position. This compound is primarily utilized in peptide synthesis as a protective group for amino acids, allowing for selective reactions without interfering with other functional groups. The Fmoc group is known for its stability under basic conditions and can be removed under mild acidic conditions, making it advantageous in synthetic protocols. The presence of the carboxylic acid functional group contributes to its solubility in polar solvents, while the aromatic structure provides rigidity and potential for π-π stacking interactions. Additionally, 4-(Fmoc-amino)benzoic acid can participate in various chemical reactions, including coupling reactions, making it a valuable intermediate in organic synthesis and medicinal chemistry. Its properties, such as melting point and solubility, can vary based on the specific conditions and purity of the compound.

Formula: C₂₂H₁₇NO₄

InChI: InChI=1/C22H17NO4/c24-21(25)14-9-11-15(12-10-14)23-22(26)27-13-20-18-7-3-1-5-16(18)17-6-2-4-8-19(17)20/h1-12,20H,13H2,(H,23,26)(H,24,25)

SMILES: c1ccc2c(c1)c1ccccc1C2COC(=O)Nc1ccc(cc1)C(=O)O

Synonyms:

• Fmoc-4-Abz-OH
• 4-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}benzoic acid
• Fmoc-4-aminobenzoic acid
• RARECHEM EM WB 0013
• FMOC-PABA-OH
• Benzoic acid, 4-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-(9CI)
• N-ALPHA-FMOC-P-AMINOBENZOIC ACID
• N-ALPHA-9-FLUORENYLMETHOXYCARBONYL-4-AMINOBENZOIC ACID
• N-FMOC-4-AMINOBENZOIC ACID
• N-ALPHA-9-FLUORENYLMETHOXYCARBONYL-P-AMINOBENZOIC ACID
• FMOC-P-ABZ-OH
• 4-(FMOC-AMINO)BENZOIC ACID 96+%
• 4-(9-FLUORENYLMETHYLOXYCARBONYL)AMINO-BENZOIC ACID

4-(Fmoc-amino)benzoic acid, 97%

CAS: 185116-43-2

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₂₂H₁₇NO₄

Purity: 97%

Molecular weight: 359.38

Ref: 02-H52828

Fmoc-4-Abz-OH

CAS: 185116-43-2

Useful as spacer in SPPS.

Formula: C₂₂H₁₇NO₄

Purity: 98.2%

Color and Shape: White Powder

Molecular weight: 359.38

Ref: 01-4027066

Fmoc-4-Abz-OH

CAS: 185116-43-2

Formula: C₂₂H₁₇NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 359.3747

Ref: IN-DA003QMO

Fmoc-4-Abz-OH

CAS: 185116-43-2

Formula: C₂₂H₁₇NO₄

Molecular weight: 359.38

Ref: 7W-GM2501

N-Fmoc-4-aminobenzoic acid

CAS: 185116-43-2

N-Fmoc-4-aminobenzoic acid

Purity: 98%

Molecular weight: 359.37g/mol

Ref: 54-OR307080

Fmoc-4-Aminobenzoic acid

CAS: 185116-43-2

Purity: 96.0%

Color and Shape: Solid

Molecular weight: 359.3810119628906

Ref: 10-F021364