Description:4-(Fmoc-amino)benzoic acid, with the CAS number 185116-43-2, is an aromatic compound characterized by the presence of a benzoic acid moiety substituted with a 9-fluorenylmethoxycarbonyl (Fmoc) group at the para position. This compound is primarily utilized in peptide synthesis as a protective group for amino acids, allowing for selective reactions without interfering with other functional groups. The Fmoc group is known for its stability under basic conditions and can be removed under mild acidic conditions, making it advantageous in synthetic protocols. The presence of the carboxylic acid functional group contributes to its solubility in polar solvents, while the aromatic structure provides rigidity and potential for π-π stacking interactions. Additionally, 4-(Fmoc-amino)benzoic acid can participate in various chemical reactions, including coupling reactions, making it a valuable intermediate in organic synthesis and medicinal chemistry. Its properties, such as melting point and solubility, can vary based on the specific conditions and purity of the compound.
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