CAS 1852-49-9
:5B-pregnane-3A-20A-diol glucuronide*crystalline
Description:
5B-pregnane-3A-20A-diol glucuronide is a steroid compound that serves as a metabolite of certain steroid hormones, particularly progesterone. It is characterized by its glucuronide conjugation, which enhances its solubility and facilitates excretion from the body. The compound is typically found in a crystalline form, indicating a well-defined molecular structure and purity. Its chemical structure includes a pregnane backbone, which is a saturated steroid framework, and the presence of hydroxyl groups at specific positions contributes to its biological activity. The glucuronide moiety is crucial for its pharmacokinetics, as it influences the compound's stability, bioavailability, and interaction with biological systems. This substance is often studied in the context of hormonal regulation, metabolism, and potential implications in reproductive health. Its CAS number, 1852-49-9, is a unique identifier that allows for precise referencing in scientific literature and databases. Overall, 5B-pregnane-3A-20A-diol glucuronide plays a significant role in the biochemistry of steroid hormones and their metabolites.
Formula:C27H44O8
InChI:InChI=1/C27H44O8/c1-13(28)17-6-7-18-16-5-4-14-12-15(8-10-26(14,2)19(16)9-11-27(17,18)3)34-25-22(31)20(29)21(30)23(35-25)24(32)33/h13-23,25,28-31H,4-12H2,1-3H3,(H,32,33)/t13-,14+,15+,16-,17+,18-,19-,20-,21-,22+,23-,25+,26-,27+/m0/s1
Synonyms:- Pregnanediol-3alpha-glucuronide
- 20alpha-Hydroxy-5beta-pregnan-3alpha-yl-beta-D-glucopyranosiduronic acid
- 5beta-Pregnane-3alpha,20alpha-diol-3alpha-glucuronide
- Pregnanediol-3-glucuronide
- (3alpha,5beta,20S)-20-Hydroxypregnan-3-yl beta-D-glucopyranosiduronic acid
- beta-D-Glucopyranosiduronic acid, (3alpha,5beta,20S)-20-hydroxypregnan-3-yl
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Found 8 products.
Pregnanediol 3α-O-β-D-glucuronide
CAS:<p>Pregnanediol 3α-O-β-D-glucuronide is a glucuronide metabolite of progesterone, which is a key steroid hormone in the reproductive system. This compound is derived from the metabolic conversion of progesterone, primarily within the liver, where it undergoes glucuronidation. This process involves the addition of glucuronic acid, mediated by the enzyme UDP-glucuronosyltransferase, enhancing the compound’s solubility for renal excretion.</p>Formula:C27H44O8Purity:Min. 95%Color and Shape:PowderMolecular weight:496.63 g/molPregnanediol 3a-O-b-D-Glucuronide
CAS:Controlled Product<p>Applications Pregnanediol 3α-O-β-D-Glucuronide is the glucuronide conjugate of Pregnanediol (P705130). Levels of Pregnanediol 3α-O-β-D-Glucuronide can be used to monitor the reproductive status of dairy cows. 3α-O-β-D-Glucuronide can be used (as an alternative to creatine) as a reference to adjust other hormonal markers in study of urinary hormonal profiles in the human menstrual cycle.<br>References Yang, C.J. et al.: Asian-Austral. J. Anim. Sci., 17, 460 (2004); Miro, F. et al.: Clin. Chem. Lab. Med., 42, 1043 (2004);<br></p>Formula:C27H44O8Color and Shape:NeatMolecular weight:496.63Pregnanediol-d5 3α-O-β-D-Glucuronide
CAS:Controlled ProductFormula:C27D5H39O8Color and Shape:NeatMolecular weight:501.664Pregnanediol 3α-O-β-D-glucuronide
CAS:<p>Pregnanediol 3α-O-β-D-glucuronide is a steroid conjugate, which is primarily a urinary metabolite derived from the catabolism of progesterone. It represents an important biomarker in endocrinological studies with direct relevance to reproductive biology. The compound originates in the body during the breakdown of progesterone, where it is conjugated with glucuronic acid to increase its solubility for renal excretion. This transformation allows for convenient and non-invasive monitoring of progesterone levels in clinical and research settings.</p>Formula:C27H44O8Purity:Min. 95 Area-%Molecular weight:496.64 g/mol
