2'-TBDMS-Bz-rC, with the CAS number 185398-21-4, is a modified nucleoside that features a 2'-O-tert-butyldimethylsilyl (TBDMS) protecting group and a benzoyl (Bz) group attached to the ribose sugar of cytidine. This compound is primarily used in the field of nucleic acid chemistry, particularly in the synthesis of oligonucleotides. The TBDMS group provides stability and protection during chemical reactions, facilitating the selective modification of nucleosides. The benzoyl group enhances the solubility and reactivity of the compound, making it suitable for various biochemical applications. Additionally, the presence of the ribose sugar indicates that this compound is a ribonucleoside, which is essential for RNA synthesis. Overall, 2'-TBDMS-Bz-rC is characterized by its protective groups that allow for controlled manipulation in synthetic pathways, contributing to advancements in molecular biology and genetic research.

2'-TBDMS-Bz-rC

185398-21-4: 2'-TBDMS-Bz-rC, with the CAS number 185398-21-4, is a modified nucleoside that features a 2'-O-tert-butyldimethylsilyl (TBDMS) protecting group and a benzoyl (Bz) group attached to the ribose sugar of cytidine. This compound is primarily used in the field of nucleic acid chemistry, particularly in the synthesis of oligonucleotides. The TBDMS group provides stability and protection during chemical reactions, facilitating the selective modification of nucleosides. The benzoyl group enhances the solubility and reactivity of the compound, making it suitable for various biochemical applications. Additionally, the presence of the ribose sugar indicates that this compound is a ribonucleoside, which is essential for RNA synthesis. Overall, 2'-TBDMS-Bz-rC is characterized by its protective groups that allow for controlled manipulation in synthetic pathways, contributing to advancements in molecular biology and genetic research.

N4-Benzoyl-2'-O-tert-butyldimethylsilylcytidine is a nucleoside that is modified by the attachment of an acetyl group at the 2' position. It is used as a component in the synthesis of oligonucleotides and can also be used in antiviral and anticancer applications. N4-Benzoyl-2'-O-tert-butyldimethylsilylcytidine is synthesized by reacting 4,5′-dihydroxybenzoic acid with 4-(dimethylamino)pyridine and diisopropylethylamine to form an intermediate, which reacts with cytosine to produce the desired product. This process requires high purity, which can be achieved through high quality production methods.

CAS 185398-21-4

2'-TBDMS-Bz-rC

N4-Benzoyl-2'-O-tert-butyldimethylsilylcytidine

Ref: 3D-NT57545