CAS 18559-94-9

Salbutamol

Description:

Salbutamol, also known as albuterol in some regions, is a selective beta-2 adrenergic agonist primarily used as a bronchodilator in the treatment of asthma and chronic obstructive pulmonary disease (COPD). Its chemical formula is C13H21NO3, and it features a phenolic hydroxyl group, which contributes to its pharmacological activity. Salbutamol works by stimulating beta-2 adrenergic receptors in the smooth muscle of the airways, leading to relaxation and dilation of bronchial passages, thereby improving airflow and alleviating symptoms of bronchospasm. The substance is typically administered via inhalation, though oral and intravenous forms are also available. Salbutamol has a relatively short half-life, necessitating multiple doses for sustained effect. It is generally well-tolerated, but potential side effects may include tremors, palpitations, and headaches. As a widely used medication, salbutamol is included in essential medicine lists and is subject to regulations regarding its use in sports due to its performance-enhancing potential.

Formula: C₁₃H₂₁NO₃

InChI: InChI=1S/C13H21NO3/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15/h4-6,12,14-17H,7-8H2,1-3H3

InChI key: InChIKey=NDAUXUAQIAJITI-UHFFFAOYSA-N

SMILES: C(CNC(C)(C)C)(O)C1=CC(CO)=C(O)C=C1

Synonyms:

• (.+-.)-Albuterol
• (.+-.)-Salbutamol
• 1,3-Benzenedimethanol, α¹-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-
• 1-(tert-Butylaminomethyl)-4-hydroxy-m-xylene-α1,α3-diol
• 1-(tert-Butylaminomethyl)-4-hydroxy-m-xylene-α¹,α³-diol
• 2-(tert-Butylamino)-1-[(4-hydroxy-3-hydroxymethyl)phenyl]ethanol
• 4-Hydroxy-3-(hydroxymethyl)-α-[[(1,1-dimethylethyl)amino]methyl]benzenemethanol
• <span class="text-smallcaps">DL</span>-N-tert-Butyl-2(4-hydroxy-3-hydroxymethylphenyl)2-hydroxyethylamine
• Ah 3365
• Airomir
• DL-N-tert-Butyl-2(4-hydroxy-3-hydroxymethylphenyl)2-hydroxyethylamine
• Eolene
• Etinoline
• ProAir HFA
• Proventil HFA
• Proventil Inhaler
• Sabumol
• Salamol EB
• Salbiar
• Saventol
• Spreor
• Sultanol
• Sultanol N
• Ventalin Inhaler
• Ventolin
• Ventoline
• Volmax
• dl-Albuterol
• dl-Salbutamol
• m-Xylene α,α'-diol, α-[(tert-butylamino)methyl]-4-hydroxy-
• m-Xylene-α,α'-diol, α1-[(tert-butylamino)methyl]-4-hydroxy-
• m-Xylene-α,α′-diol, α¹-[(tert-butylamino)methyl]-4-hydroxy-
• α1-tert-Butylaminomethyl-4-hydroxy-m-xylene-α1,α3-diol
• α¹-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol
• α¹-tert-Butylaminomethyl-4-hydroxy-m-xylene-α¹,α³-diol
• α1-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol

(±)-Salbutamol

Controlled Product

CAS: 18559-94-9

(±)-Salbutamol is a racemic mixture of a beta-2 adrenergic agonist, which is synthetically derived. This compound functions primarily by selectively stimulating beta-2 adrenergic receptors, which are predominantly located on the smooth muscle cells lining the airways. The activation of these receptors leads to the relaxation of bronchial muscle tissue, resulting in bronchodilation and improved airflow.

Formula: C₁₃H₂₁NO₃

Molecular weight: 239.31 g/mol

Ref: 3D-Q-201695