The chemical substance known as (3beta,5alpha)-3,17-dihydroxy-11,20-dioxopregnan-21-yl acetate, with the CAS number 1856-12-8, is a steroid derivative that exhibits specific structural and functional characteristics typical of steroid hormones. This compound features a pregnane backbone, which is a 21-carbon steroid structure, and includes hydroxyl (-OH) groups at the 3 and 17 positions, contributing to its reactivity and biological activity. The presence of dioxo groups at the 11 and 20 positions indicates that it has two ketone functionalities, which can influence its interaction with biological receptors. The acetate group at the 21 position suggests that this compound may have enhanced lipophilicity, potentially affecting its absorption and distribution in biological systems. Such structural features often correlate with hormonal activity, particularly in the context of glucocorticoids or progestins. Overall, this compound is of interest in pharmacology and biochemistry for its potential roles in various physiological processes and therapeutic applications.

(3beta,5alpha)-3,17-dihydroxy-11,20-dioxopregnan-21-yl acetate

1856-12-8: The chemical substance known as (3beta,5alpha)-3,17-dihydroxy-11,20-dioxopregnan-21-yl acetate, with the CAS number 1856-12-8, is a steroid derivative that exhibits specific structural and functional characteristics typical of steroid hormones. This compound features a pregnane backbone, which is a 21-carbon steroid structure, and includes hydroxyl (-OH) groups at the 3 and 17 positions, contributing to its reactivity and biological activity. The presence of dioxo groups at the 11 and 20 positions indicates that it has two ketone functionalities, which can influence its interaction with biological receptors. The acetate group at the 21 position suggests that this compound may have enhanced lipophilicity, potentially affecting its absorption and distribution in biological systems. Such structural features often correlate with hormonal activity, particularly in the context of glucocorticoids or progestins. Overall, this compound is of interest in pharmacology and biochemistry for its potential roles in various physiological processes and therapeutic applications.

<p>Applications 3β,17,21-trihydroxy-5α-Pregnane-11,20-dione 21-Acetate can be used to synthesize 5α-pregnane-3β, 17α,21-triol-11,20-dione (Reichstein's substance D) and 5α-pregnane-3β, 11β,17α,21-tetrol-20-one (Reichstein's substance V).<br>References Chamberlin, E., et al.: J. Amer. Chem. Soc., 77, 1221 (1955);<br></p>

CAS 1856-12-8

(3beta,5alpha)-3,17-dihydroxy-11,20-dioxopregnan-21-yl acetate

3β,17,21-Trihydroxy-5α-Pregnane-11,20-dione 21-Acetate

Ref: TR-T795255