CAS 186033-14-7

2-Amino-5-(2-fluorophenyl)-4-methyl-1H-pyrrole-3-carbonitrile

Description:

2-Amino-5-(2-fluorophenyl)-4-methyl-1H-pyrrole-3-carbonitrile is a chemical compound characterized by its unique pyrrole structure, which includes an amino group, a carbonitrile group, and a fluorophenyl substituent. The presence of the amino group contributes to its potential as a building block in pharmaceuticals and agrochemicals, while the carbonitrile group can enhance its reactivity and solubility in various solvents. The fluorophenyl moiety may influence the compound's electronic properties and biological activity, making it of interest in medicinal chemistry. This compound is likely to exhibit moderate to high polarity due to the presence of polar functional groups, which can affect its solubility and interaction with biological systems. Additionally, the presence of the methyl group at the 4-position of the pyrrole ring may influence steric hindrance and overall molecular conformation. Overall, this compound's structural features suggest potential applications in drug development and material science, although specific biological activities and properties would require further investigation through experimental studies.

Formula: C₁₂H₁₀FN₃

Synonyms:

• Ns-8

2-Amino-5-(2-fluorophenyl)-4-methyl-1H-pyrrole-3-carbonitrile

Controlled Product

CAS: 186033-14-7

Applications 2-amino-5-(2-fluorophenyl)-4-methyl-1H-pyrrole-3-carbonitrile (cas# 186033-14-7) is used as calcium-activated potassium channel (BKCa) activator for treating muscular disorder.
References Selwood, D., et al.: PCT Int. Appl. 44 pp. (2016)

Formula: C₁₂H₁₀FN₃

Color and Shape: Neat

Molecular weight: 215.226

Ref: TR-A639345

2-Amino-5-(2-fluorophenyl)-4-methyl-1H-pyrrole-3-carbonitrile

CAS: 186033-14-7

2-Amino-5-(2-fluorophenyl)-4-methyl-1H-pyrrole-3-carbonitrile is a white crystalline powder that has a pyrrole ring structure. It has been found to be stable in air and light, but not soluble in water. The infrared absorption spectrum of this compound shows bands at 3140 cm−1, 1650 cm−1, 1560 cm−1, and 880 cm−1. 2-Amino-5-(2-fluorophenyl)-4-methyl-1H-pyrrole-3-carbonitrile is not soluble in water but can be dissolved in methanol or ethanol. It is an organic chemical with a molecular weight of 198.2 g/mol and a melting point of 184°C.

Formula: C₁₂H₁₀FN₃

Purity: Min. 95%

Molecular weight: 215.23 g/mol

Ref: 3D-LHA03314

NS-8

CAS: 186033-14-7

NS-8, a pyrrole, activates Ca2+-sensitive K+ channels, reducing urinary frequency by inhibiting pelvic nerve activity.

Formula: C₁₂H₁₀FN₃

Color and Shape: Solid

Molecular weight: 215.23

Ref: TM-T73572