CAS 186319-72-2

β-Amyloid (1-17)

Description:

β-Amyloid (1-17), with the CAS number 186319-72-2, is a peptide fragment derived from the amyloid precursor protein (APP) and is primarily associated with Alzheimer's disease. This peptide consists of the first 17 amino acids of the β-amyloid peptide, which is known for its role in the formation of amyloid plaques in the brains of Alzheimer's patients. The characteristics of β-Amyloid (1-17) include its hydrophilic nature, which influences its solubility and interactions with other biomolecules. It is typically studied for its potential neurotoxic effects and its role in the pathophysiology of neurodegenerative diseases. The peptide can undergo aggregation, leading to the formation of oligomers and fibrils, which are implicated in neuronal damage. Additionally, β-Amyloid (1-17) can interact with various receptors and proteins in the brain, affecting synaptic function and signaling pathways. Research on this peptide is crucial for understanding the mechanisms of Alzheimer's disease and developing therapeutic strategies to mitigate its effects.

Formula: C₉₀H₁₃₀N₂₈O₂₉

Synonyms:

• β-Amyloid 1-17
• β-Amyloid (1-17)
• L-Leucine, L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-α-aspartyl-L-serylglycyl-L-tyrosyl-L-α-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-

β-Amyloid (1-17)

CAS: 186319-72-2

This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.

Formula: C₉₀H₁₃₀N₂₈O₂₉

Purity: 98%

Color and Shape: Solid

Molecular weight: 2068.2

Ref: TM-TP1500