CAS 186350-56-1

N-alpha-Allyloxycarbonyl-N-epsilon-(9-fluorenylmethyloxycarbonyl)-L-lysine

Description:

N-alpha-Allyloxycarbonyl-N-epsilon-(9-fluorenylmethyloxycarbonyl)-L-lysine, commonly referred to as a protected form of the amino acid lysine, is a compound used primarily in peptide synthesis and bioconjugation. This substance features two protective groups: the allyloxycarbonyl (Alloc) group at the alpha position and the 9-fluorenylmethyloxycarbonyl (Fmoc) group at the epsilon position of the lysine side chain. These protective groups are crucial for selectively modifying the amino acid during synthetic processes, allowing for the controlled assembly of peptides without unwanted side reactions. The presence of the fluorenyl group provides stability and facilitates purification through chromatographic techniques. Additionally, the compound is typically soluble in organic solvents, making it suitable for various chemical reactions. Its structure allows for the selective deprotection of the amino groups under specific conditions, enabling the synthesis of complex peptides and proteins. Overall, this compound is valuable in the field of organic chemistry and biochemistry for its role in facilitating peptide synthesis and modifications.

Formula: C₂₅H₂₈N₂O₆

Synonyms:

• Alloc-Lys(Fmoc)-OH
• (2S)-6-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-{[(prop-2-en-1-yloxy)carbonyl]amino}hexanoic acid
• N-alpha-Allyloxycarbonyl-N-epsilon-(9-fluorenylmethyloxycarbonyl)-L-lysine
• N-alpha-Allyloxycarbonyl-N-epsilon-(9-fluorenylmethyloxycarbonyl)-L-lysine USP/EP/BP
• N6-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N2-((allyloxy)carbonyl)-L-lysine
• Aloc-L-Lys(Fmoc)-OH
• Alloc-L-Lysine (fmoc)
• N-alpha-Allyloxycarbonyl-N-epsilon-2-Fmoc-L-lysine
• N-α-Allyloxycarbonyl-N-ε-(9-fluorenylmethoxycarbonyl)-L-lysine
• N6-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N2-[(2-propenyloxy)carbonyl]-L-lysine
• L-Lysine, N6-[(9H-fluoren-9-ylmethoxy)carbonyl]-N2-[(2-propen-1-yloxy)carbonyl]-
• N6-Fmoc-N2-(allyloxycarbonyl)-L-lysine

N6-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N2-[(2-propenyloxy)carbonyl]-L-lysine

CAS: 186350-56-1

Formula: C₂₅H₂₈N₂O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 452.4996

Ref: IN-DA003967

N6-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N2-((allyloxy)carbonyl)-L-lysine

CAS: 186350-56-1

N6-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N2-((allyloxy)carbonyl)-L-lysine

Purity: 98%

Molecular weight: 452.51g/mol

Ref: 54-OR73446

Alloc-l-Lysine (fmoc)

CAS: 186350-56-1

Formula: C₂₅H₂₈N₂O₆

Purity: 97%

Color and Shape: Solid

Molecular weight: 452.507

Ref: 10-F046648

N-α-Allyloxycarbonyl-N-ε-2-Fmoc-L-lysine

CAS: 186350-56-1

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Formula: C₂₅H₂₈N₂O₆

Molecular weight: 452.5 g/mol

Ref: 3D-A-9750

N-alpha-Allyloxycarbonyl-N-epsilon-2-Fmoc-L-lysine

CAS: 186350-56-1

The synthesis of semaglutide is accomplished by a solid-phase synthetic route. The peptide is synthesized on a polymeric support. The side chains are assembled in the liquid phase and then condensed with the peptide chain. The condensation reaction between the side chains and peptide chain is catalyzed by an acid such as trifluoroacetic acid or ethyl chloroformate. Semaglutide was synthesized using this method to produce high purity, concentration, and yield.

Formula: C₂₅H₂₈N₂O₆

Purity: Min. 95%

Color and Shape: White/Off-White Solid

Molecular weight: 452.5 g/mol

Ref: 3D-FA49854