Description:1,1'-Oxalyldiimidazole is a chemical compound characterized by its unique structure, which consists of two imidazole rings connected by an oxalyl group. This compound is often utilized as a coupling agent in peptide synthesis and other organic reactions due to its ability to activate carboxylic acids for amide bond formation. It is a white to off-white solid that is soluble in polar organic solvents. The presence of imidazole rings contributes to its reactivity, making it a versatile reagent in various chemical transformations. Additionally, 1,1'-Oxalyldiimidazole is known for its stability under standard laboratory conditions, although it should be handled with care due to its potential reactivity with moisture and other nucleophiles. Its applications extend beyond peptide synthesis, including use in the preparation of other nitrogen-containing compounds. As with many chemical substances, appropriate safety measures should be taken when handling this compound, including the use of personal protective equipment and working in a well-ventilated area.
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