CAS 186392-40-5

CP 91149

Description:

CP 91149, with the CAS number 186392-40-5, is a chemical compound that belongs to the class of small molecules. It is primarily recognized for its role as a selective inhibitor of certain protein kinases, which makes it of interest in pharmaceutical research, particularly in the context of cancer therapy. The compound exhibits specific binding affinity to its target enzymes, influencing various cellular signaling pathways. CP 91149 is characterized by its unique molecular structure, which contributes to its biological activity. It is typically studied in vitro and in vivo to assess its efficacy and safety profile. As with many chemical substances, handling CP 91149 requires adherence to safety protocols due to potential toxicity and environmental impact. Its solubility, stability, and reactivity are important factors that influence its application in research and development. Overall, CP 91149 represents a significant compound in the ongoing exploration of targeted therapies in oncology and related fields.

Formula: C₂₁H₂₁ClN₃O₃

InChI: InChI=1S/C21H22ClN3O3/c1-25(2)21(28)19(26)17(10-13-6-4-3-5-7-13)24-20(27)18-12-14-11-15(22)8-9-16(14)23-18/h3-9,11-12,17,19,23,26H,10H2,1-2H3,(H,24,27)/t17-,19+/m0/s1

Synonyms:

• 5-Chloro-N-[(2S,3R)-4-(dimethylamino)-3-hydroxy-4-oxo-1-phenyl-2-butanyl]-1H-indole-2-carboxamide
• (2R,3S)-3-[(5-Chloro-1H-indol-2-yl)formamido]-2-hydroxy-N,N-dimethyl-4-phenylbutanamide
• 5-chloro-N-((2S,3R)-4-(dimethylamino)-3-hydroxy-4-oxo-1-phenylbutan-2-yl)-1H-indole-2-carboxamide
• CP 91149
• [R-(R*,S*)]-5-Chloro-N-[3-(diMethylaMino)-2-hydroxy-3-oxo-
• 1-(phenylMethyl)propyl]-1H-indole-2-carboxaMide
• 5-Chloro-N-[(1S,2R)-3-(diMethylaMino)-2-hydroxy-3-oxo-1-(phenylMethyl)propyl]-1H-indole-2-carboxaMide
• CP 91149 USP/EP/BP
• CS-231

CP 91149

CAS: 186392-40-5

Formula: C₂₁H₂₂ClN₃O₃

Purity: 99%

Color and Shape: Solid

Molecular weight: 399.8707

Ref: IN-DA00ADJN

CP-91149

CAS: 186392-40-5

CP-91149

Purity: ≥98%

Molecular weight: 399.87g/mol

Ref: 54-BUP13123

CP-91149

CAS: 186392-40-5

Formula: C₂₁H₂₂ClN₃O₃

Molecular weight: 399.87

Ref: 7W-GK6711

CP-91149

CAS: 186392-40-5

Formula: C₂₁H₂₂ClN₃O₃

Molecular weight: 399.88

Ref: 4Z-K-031021

CP-91149

CAS: 186392-40-5

CP-91149 is a selective glycogen phosphorylase (GP) inhibitor with IC50 of 0.13 μM in the presence of glucose, 5- to 10-fold less potent in the absence of

Formula: C₂₁H₂₂ClN₃O₃

Purity: 99.66% - 99.81%

Color and Shape: Solid

Molecular weight: 399.87

Ref: TM-T6455

CP-91149

CAS: 186392-40-5

Stability Hygroscopic
Applications Inhibition of glycogen phosphorylase (GP) by CP-91,149 induces growth inhibition correlating with brain GP expression. Antitumor agent.
References Newgard, C., et al.: J. Biol. Chem., 263, 3850 (1988), Ignacio, P., et al.: Brain Res., 529, 42 (1990), Oikonomakos, N., et al.: J. Biol. Chem., 275, 34566 (2000), Pedersen, B., et al.: J. Biol. Chem., 275, 27753 (2000),

Formula: C₂₁H₂₂ClN₃O₃

Color and Shape: Neat

Molecular weight: 399.8707

Ref: TR-C781360

CP 91149

CAS: 186392-40-5

Inhibitor of glycogen phosphorylase

Formula: C₂₁H₂₂ClN₃O₃

Purity: Min. 95%

Molecular weight: 399.87 g/mol

Ref: 3D-FC20583