CAS 1865-01-6

4-Nitrophenyl formate

Description:

4-Nitrophenyl formate, with the CAS number 1865-01-6, is an organic compound characterized by its structure, which includes a nitro group (-NO2) attached to a phenyl ring and a formate group (-OCHO). This compound is typically a pale yellow solid at room temperature and is soluble in organic solvents such as ethanol and acetone, but less soluble in water. It is known for its use in organic synthesis, particularly as an intermediate in the preparation of various pharmaceuticals and agrochemicals. The presence of the nitro group enhances its reactivity, making it a useful building block in chemical reactions, including nucleophilic substitutions and coupling reactions. Additionally, 4-nitrophenyl formate can exhibit certain biological activities, which may be of interest in medicinal chemistry. As with many nitro compounds, it should be handled with care due to potential toxicity and environmental concerns. Proper safety measures, including the use of personal protective equipment, are recommended when working with this substance.

Formula: C₇H₅NO₄

InChI: InChI=1S/C7H5NO4/c9-5-12-7-3-1-6(2-4-7)8(10)11/h1-5H

InChI key: InChIKey=IEXRKQFZXJSHOB-UHFFFAOYSA-N

SMILES: N(=O)(=O)C1=CC=C(OC=O)C=C1

Synonyms:

• Formic acid 4-nitrophenyl ester
• Formic acid, p-nitrophenyl ester
• NSC 154301
• p-Nitrophenyl formate
• 4-Nitrophenyl formate

4-Nitrophenyl formate, 98%

CAS: 1865-01-6

Convenient and selective reagent for the selective formylation of terminal amino groups in such basic amino acids as ornithine or lysine and formylation of -amino groups in peptides. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some document

Formula: C₇H₅NO₄

Purity: 98%

Color and Shape: Crystals or powder or crystalline powder or fused solid, White to cream to pale yellow

Molecular weight: 167.12

Ref: 02-L00316

4-Nitrophenyl formate

CAS: 1865-01-6

Formula: C₇H₅NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 167.1189

Ref: IN-DA003LVZ

4-Nitrophenyl Formate

CAS: 1865-01-6

4-Nitrophenyl Formate

Purity: 95%

Molecular weight: 167.12g/mol

Ref: 54-OR1011634

p-Nitrophenyl formate

CAS: 1865-01-6

p-Nitrophenyl formate is a supramolecular compound that has been used as a model protein to study protein synthesis. It is an acylation reaction product of p-nitrophenol and formic acid, which can be synthesized in the laboratory by heating p-nitrophenol with formic acid. p-Nitrophenyl formate binds to messenger RNA (mRNA) and inhibits translation of the mRNA into proteins. This leads to decreased bacterial growth and inhibition of cell division. p-Nitrophenyl formate also has hydrogen bonding properties that make it useful for immobilization purposes. The compound is unsymmetrical, which makes it difficult to synthesize using traditional methods, but can be made using the Fischer esterification reaction.

Formula: C₇H₅NO₄

Purity: Min. 96.0 Area-%

Color and Shape: Powder

Molecular weight: 167.12 g/mol

Ref: 3D-FN26324

p-Nitrophenyl Formate

CAS: 1865-01-6

Formula: C₇H₅NO₄

Purity: 98%

Color and Shape: Crystalline

Molecular weight: 167.12

Ref: 10-F341922