CAS 186544-26-3

N-[(3R)-3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamide

Description:

N-[(3R)-3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamide, with CAS number 186544-26-3, is a chemical compound characterized by its complex structure, which includes a carbazole moiety and a fluorobenzamide group. This compound features a chiral center, indicated by the (3R) configuration, which can influence its biological activity and interactions. The presence of a dimethylamino group suggests potential for basicity and involvement in hydrogen bonding, while the fluorine atom in the benzamide portion may enhance lipophilicity and metabolic stability. Such structural characteristics often contribute to the compound's pharmacological properties, making it of interest in medicinal chemistry, particularly in the development of pharmaceuticals targeting specific biological pathways. Its unique combination of functional groups may also affect solubility, reactivity, and overall stability in various environments. As with many compounds in this category, safety and handling precautions are essential due to potential biological activity and toxicity.

Formula: C₂₁H₂₂FN₃O

InChI: InChI=1S/C21H22FN3O/c1-25(2)16-8-10-20-18(12-16)17-11-15(7-9-19(17)24-20)23-21(26)13-3-5-14(22)6-4-13/h3-7,9,11,16,24H,8,10,12H2,1-2H3,(H,23,26)/t16-/m1/s1

InChI key: InChIKey=GKWHICIUSVVNGX-MRXNPFEDSA-N

SMILES: N(C)(C)[C@H]1CC=2C=3C(NC2CC1)=CC=C(NC(=O)C4=CC=C(F)C=C4)C3

Synonyms:

• Benzamide, N-[(3R)-3-(dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluoro-
• Benzamide, N-[3-(dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluoro-, (R)-
• Ly 344864
• Ly344864
• N-[(3R)-3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamide
• N-[(3R)-3-(dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluoro-benzamide

LY 344864

CAS: 186544-26-3

LY 344864

Purity: ≥98%

Molecular weight: 351.42g/mol

Ref: 54-BUP05774

LY 344864

CAS: 186544-26-3

LY 344864, a specifc receptor agonist, is an affinity of 6 nM (Ki) at the recently cloned 5-HT1F receptor.

Formula: C₂₁H₂₂FN₃O

Purity: 98%

Color and Shape: Solid

Molecular weight: 351.42

Ref: TM-T2344