CAS 18656-40-1

Dilauroylphosphatidylcholine

Description:

Dilauroylphosphatidylcholine (DLPC) is a synthetic phospholipid that is commonly used in biochemical and biophysical research. It is characterized by its two lauric acid (dodecanoic acid) chains attached to a glycerol backbone, with a choline head group. This structure imparts amphiphilic properties, allowing DLPC to form lipid bilayers and vesicles in aqueous environments, making it valuable for studies involving membrane dynamics and drug delivery systems. DLPC is typically found in a liquid crystalline state at physiological temperatures, which contributes to its fluidity and flexibility in membrane applications. Additionally, it is known for its role in stabilizing proteins and other biomolecules in solution. The compound is soluble in organic solvents and has limited solubility in water, which is typical for phospholipids. Due to its biocompatibility and ability to mimic natural cell membranes, DLPC is often utilized in the formulation of liposomes and other nanocarriers for therapeutic agents. Its unique properties make it a significant tool in the fields of membrane biology and pharmaceutical development.

Formula: C₃₂H₆₄NO₈P

InChI: InChI=1S/C32H64NO8P/c1-6-8-10-12-14-16-18-20-22-24-31(34)38-28-30(29-40-42(36,37)39-27-26-33(3,4)5)41-32(35)25-23-21-19-17-15-13-11-9-7-2/h30H,6-29H2,1-5H3

InChI key: InChIKey=IJFVSSZAOYLHEE-UHFFFAOYSA-N

SMILES: C(COP(OCC[N+](C)(C)C)(=O)[O-])(COC(CCCCCCCCCCC)=O)OC(CCCCCCCCCCC)=O

Synonyms:

• 1,2-Didodecanoyl-rac-glycero-3-phosphocholine
• 1,2-Didodecanoylphosphatidylcholine
• 1,2-Dilauroyl-rac-glycero-3-phosphocholine
• 1,2-Dilauroylglycerol-3-phosphorylcholine
• 3,5,9-Trioxa-4-phosphaheneicosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxododecyl)oxy]-, inner salt, 4-oxide
• <span class="text-smallcaps">D</smallcap><smallcap>L</span>-Dilauroylphosphatidylcholine
• Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-dilaurin, <span class="text-smallcaps">DL</span>-
• Didodecanoylglycerophosphorylcholine
• Didodecanoylphosphatidylcholine
• Dilauroyl lecithin
• Dilauroyl phosphatidylcholine
• Dilauroylglycerophosphocholine
• Dilauroylglyceryl-3-phosphorylcholine
• Dilauroylglycerylphosphorylcholine
• Dilauroylphosphatidylcholine
• Laurin, 1,2-di-, dihydrogen phosphate, monoester with choline hydroxide, inner salt, <span class="text-smallcaps">DL</span>-
• dl-A-phosphatidylcholine,*dilauroyl (C12:0)
• rac-DLPC
• Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-dilaurin, DL-

1,2-Dilauroyl-sn-Glycero-3-Phosphatidylcholine

CAS: 18656-40-1

Formula: C32H64NO8P

Purity: >99%

Color and Shape: Solid

Molecular weight: 621.83

Ref: 48-37-1200

1,2-Dilauroyl-rac-glycero-3-phosphocholine

CAS: 18656-40-1

1,2-Dilauroyl-rac-glycero-3-phosphocholine (DLPC) is a synthetic phospholipid that exhibits significant cytotoxicity against hyperproliferative cells. DLPC has been shown to inhibit the activity of the enzyme sphingosine 2-phosphate (S2P) and cell factor, both of which are important in signal transduction pathways. DLPC is capable of inducing phase transition at a temperature close to body temperature, making it biocompatible for use as a topical or injectable drug. It has also been shown to be effective in treating infectious diseases such as HIV and malaria, due to its ability to bind with basic proteins found on the surface of these viruses.

Formula: C₃₂H₆₄NO₈P

Purity: Min. 95%

Molecular weight: 621.83 g/mol

Ref: 3D-FD111153

1,2-Dilauroyl-rac-glycero-3-phosphocholine

CAS: 18656-40-1

Bachem ID: 4018411.

Formula: C₃₂H₆₄NO₈P

Purity: > 98%

Color and Shape: White Powder

Molecular weight: 621.84

Ref: 01-4018411