CAS 1866-15-5

Acetylthiocholine iodide

Description:

Acetylthiocholine iodide is a quaternary ammonium compound that serves as a substrate for the enzyme acetylcholinesterase and is often used in biochemical research, particularly in studies related to neurotransmission. It is a synthetic analog of the neurotransmitter acetylcholine, featuring a thioether group that enhances its stability and reactivity. The compound is typically a white to off-white crystalline solid, soluble in water and polar organic solvents. Its structure includes an acetyl group attached to a thiocholine moiety, which contributes to its ability to mimic acetylcholine's action at cholinergic receptors. Acetylthiocholine iodide is commonly utilized in assays to measure enzyme activity and in pharmacological studies to investigate cholinergic signaling pathways. Due to its quaternary nature, it does not readily cross biological membranes, making it useful for in vitro studies. Safety precautions should be observed when handling this compound, as it may pose health risks if ingested or inhaled.

Formula: C₇H₁₆NOS·I

InChI: InChI=1S/C7H16NOS.HI/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1

InChI key: InChIKey=NTBLZMAMTZXLBP-UHFFFAOYSA-M

SMILES: C(CSC(C)=O)[N+](C)(C)C.[I-]

Synonyms:

• (2-Mercaptoethyl)trimethylammonium iodide acetate
• 2-(Acetylsulfanyl)-N,N,N-trimethylethanaminium iodide
• 2-Acetylthioethyltrimethylammonium Iodide
• Acetic acid, thio-, S-ester with (2-mercaptoethyl)trimethylammonium iodide
• Acetylthiocholine diiodide
• Acetylthiocholine iodide
• Ammonium, (2-mercaptoethyl)trimethyl-, iodide, acetate
• Ethanaminium, 2-(acetylthio)-N,N,N-trimethyl-, iodide
• [2-(Acetylsulfanyl)ethyl]trimethylazanium iodide
• [2-(Acetylthio)ethyl](trimethyl)ammonium iodide
• ethanaminium, 2-(acetylthio)-N,N,N-trimethyl-, iodide (1:1)

Acetylthiocholine Iodide

CAS: 1866-15-5

Formula: C₇H₁₆INOS

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 289.18

Ref: 3B-A0116

Acetylthiocholine iodide

CAS: 1866-15-5

Formula: C₇H₁₆INOS

Purity: 98%

Color and Shape: Solid, White - Almost white powder

Molecular weight: 289.18

Ref: 10-F228086

S-Acetylthiocholine iodide, 98%

CAS: 1866-15-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₁₆INOS

Purity: 98%

Color and Shape: White, Crystals or powder or crystalline powder

Molecular weight: 289.18

Ref: 02-A16802

Ethanaminium, 2-(acetylthio)-N,N,N-trimethyl-, iodide

CAS: 1866-15-5

Formula: C₇H₁₆INOS

Purity: 98%

Color and Shape: Solid

Molecular weight: 289.1775

Ref: IN-DA00I1TX

Acetylthiocholine iodide

CAS: 1866-15-5

Formula: C₇H₁₆INOS

Purity: (Titration) ≥ 98.0%

Color and Shape: White or almost white crystalline powder

Molecular weight: 289.18

Ref: 7W-GE4789

[2-(acetylthio)ethyl](trimethyl)ammonium iodide

CAS: 1866-15-5

[2-(acetylthio)ethyl](trimethyl)ammonium iodide

Purity: 98%

Molecular weight: 289.1775g/mol

Ref: 54-OR27854

S-Acetylthiocholine iodide

CAS: 1866-15-5

S-Acetylthiocholine iodide

Formula: C₇H₁₆NOS·I

Purity: 98%

Color and Shape: white solid

Molecular weight: 289.1775g/mol

Ref: 54-BIA4001

Acetylthiocholine Iodide

Controlled Product

CAS: 1866-15-5

Applications Acetylthiocholine Iodide functions as a potential biomarkers for the dictation of diseases or biological conditions (in-vitro) in marines and also functions in ecotoxically studies in marine.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gomes, I. D. L., et al.: Mar. Pollut.Bull. (2014), 85(1), 179-185

Formula: C₇H₁₆NOS·I

Color and Shape: Neat

Molecular weight: 289.1775

Ref: TR-A164610

S-Acetylthiocholine iodide

CAS: 1866-15-5

S-Acetylthiocholine iodide is an acetylcholinesterase substrate for the colorimetric determination of acetylcholinesterase activity. In this assay the production of thiocholine formed in the hydrolysis of acetylthiocholine is measured by coupling of the reactive thiol with DTNB to give a thionitrobenzoate (TNB). The TNB is a yellow anion and its formation can be measured spectrometrically. Nicotinic acetylcholine receptor agonist.

Formula: C₇H₁₆INOS

Molecular weight: 289.18 g/mol

Ref: 3D-A-1700

S-Acetylthiocholine iodide

CAS: 1866-15-5

S-Acetylthiocholine iodide is an inhibitor of acetylcholinesterase. This compound has been shown to be effective in a variety of biochemical and experimental models, with the optimum concentration at 5-10 mM. S-Acetylthiocholine iodide has also been shown to have inhibitory properties against other enzymes, such as brain functions and choline esterase. The inhibition of these enzymes may lead to the development of novel biomarkers for the diagnosis of diseases such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis.

Formula: C₇H₁₆INOS

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 289.18 g/mol

Ref: 3D-FA33157

S-Acetylthiocholine Iodide extrapure AR, 99%

CAS: 1866-15-5

Formula: C₇H₁₆NOSI

Purity: min. 99%

Color and Shape: White to off - white, Crystalline powder, Clear

Molecular weight: 289.17

Ref: SR-38998