CAS 1866-43-9

Rolodine

Description:

Rolodine, with the CAS number 1866-43-9, is a chemical compound that belongs to the class of antihistamines. It is primarily characterized by its ability to act as a histamine H1 receptor antagonist, which makes it useful in alleviating allergic reactions and symptoms such as itching, sneezing, and runny nose. Rolodine exhibits a relatively low solubility in water, which can influence its bioavailability and pharmacokinetics. The compound is typically administered in various formulations, including tablets and syrups, and is known for its sedative properties, which can lead to drowsiness in some individuals. Its chemical structure includes specific functional groups that contribute to its pharmacological activity. As with many antihistamines, potential side effects may include dry mouth, dizziness, and gastrointestinal disturbances. It is important to use Rolodine under medical supervision to ensure safety and efficacy, particularly in populations such as children or those with pre-existing health conditions.

Formula: C₁₄H₁₄N₄

InChI: InChI=1S/C14H14N4/c1-10-17-13-12(7-8-15-13)14(18-10)16-9-11-5-3-2-4-6-11/h2-8H,9H2,1H3,(H2,15,16,17,18)

InChI key: InChIKey=HPZHFGBKCGWNGN-UHFFFAOYSA-N

SMILES: N(CC1=CC=CC=C1)C2=C3C(=NC(C)=N2)NC=C3

Synonyms:

• BW 58 271
• 7H-Pyrrolo[2,3-d]pyrimidine, 4-(benzylamino)-2-methyl-
• 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 2-methyl-N-(phenylmethyl)-
• 4-(Benzylamino)-2-methyl-7H-pyrrolo[2,3-d]pyrimidine
• 2-Methyl-N-(phenylmethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine