CAS 186792-80-3
:OLANZAPINE GLUCURONIDE
Description:
Olanzapine glucuronide is a metabolite of the antipsychotic medication olanzapine, which is primarily used to treat schizophrenia and bipolar disorder. This compound is formed through the process of glucuronidation, where a glucuronic acid moiety is conjugated to olanzapine, enhancing its solubility and facilitating excretion from the body. The chemical structure of olanzapine glucuronide retains the core pharmacophore of olanzapine but is modified to include the glucuronic acid, which alters its pharmacokinetic properties. As a result, olanzapine glucuronide is generally less active than its parent compound in terms of antipsychotic effects. Its presence in biological fluids can be indicative of olanzapine metabolism and is often monitored in pharmacokinetic studies. The compound is typically characterized by its solubility in polar solvents and may exhibit different stability profiles compared to olanzapine. Understanding its characteristics is crucial for evaluating the overall pharmacological profile and safety of olanzapine therapy.
Formula:C23H30N4O7S
Synonyms:- 1-Deoxy-1-[2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepin-10-yl]-b-D-glucopyranuronic Acid
- Olanzapine-b-D-glucuronide
- 1-Deoxy-1-[2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepin-10-yl]--D-glucopyranuronic Acid
Sort by
The purity filter is not visible because current products do not have associated purity data for filtering.
Found 2 products.
