CAS 18684-63-4

bicyclo[2.2.2]octan-7-ol

Description:

Bicyclo[2.2.2]octan-7-ol, with the CAS number 18684-63-4, is a bicyclic organic compound characterized by its unique structure, which consists of a bicyclo[2.2.2]octane framework with a hydroxyl (-OH) group attached at the 7-position. This compound is a colorless to pale yellow liquid or solid, depending on the temperature and purity. It is known for its relatively high stability due to the rigid bicyclic structure, which limits conformational flexibility. Bicyclo[2.2.2]octan-7-ol exhibits moderate polarity, making it soluble in polar solvents while having limited solubility in non-polar solvents. The presence of the hydroxyl group contributes to its potential as a hydrogen bond donor, influencing its reactivity and interactions with other molecules. This compound may find applications in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals, due to its unique structural properties. Additionally, its derivatives can serve as intermediates in various chemical reactions, showcasing its versatility in synthetic chemistry.

Formula: C₈H₁₄O

InChI: InChI=1/C8H14O/c9-8-5-6-1-3-7(8)4-2-6/h6-9H,1-5H2

SMILES: C1CC2CCC1CC2O

Synonyms:

• Bicyclo(2.2.2)octan-2-ol
• bicyclo[2.2.2]octan-7-ol
• (R)-Qinoclidinole

bicyclo[2.2.2]octan-7-ol

CAS: 18684-63-4

Formula: C₈H₁₄O

Purity: 97%

Color and Shape: Solid

Molecular weight: 126.1962

Ref: IN-DA00AKH4

Bicyclo[2.2.2]octan-2-ol

CAS: 18684-63-4

Bicyclo[2.2.2]octan-2-ol

Purity: 95%

Molecular weight: 126.2g/mol

Ref: 54-OR1051485

Bicyclo[2.2.2]octan-2-ol

CAS: 18684-63-4

Formula: C₈H₁₄O

Purity: 97.0%

Color and Shape: Solid, No data available.

Molecular weight: 126.199

Ref: 10-F424650

Bicyclo[2.2.2]octan-2-ol

Controlled Product

CAS: 18684-63-4

Formula: C₈H₁₄O

Color and Shape: Neat

Molecular weight: 126.196

Ref: TR-B593198

Bicyclo[2.2.2]octan-2-ol

CAS: 18684-63-4

Bicyclo[2.2.2]octan-2-ol is an antiplasmodial agent that is used to treat malaria caused by Plasmodium falciparum and P. vivax. It binds to the parasite's heme, preventing its conversion of heme to protoporphyrin IX and blocking the synthesis of ATP, leading to cell death. Bicyclo[2.2.2]octan-2-ol has also been shown to be effective against multiresistant strains of plasmodium and has a low toxicity in humans. This substance can be synthesized by epimerization of 2-(bromomethyl)cyclohexanol with maleic anhydride or 2-benzoylcyclohexanol with benzoic acid. The yields from these reactions are low, but the product can be easily tracked due to its distinctive chemical properties (e.g., high boiling point

Formula: C₈H₁₄O

Purity: Min. 95%

Molecular weight: 126.2 g/mol

Ref: 3D-TAA68463