CAS 18694-40-1

Epirizole

Description:

Epirizole, with the CAS number 18694-40-1, is a chemical compound that belongs to the class of non-steroidal anti-inflammatory drugs (NSAIDs). It is primarily recognized for its analgesic and anti-inflammatory properties. Epirizole is characterized by its ability to inhibit cyclooxygenase enzymes, which play a crucial role in the biosynthesis of prostaglandins, thereby reducing pain and inflammation. The compound is typically administered in various formulations, including tablets and injections, depending on the therapeutic needs. Its pharmacokinetics involve absorption, distribution, metabolism, and excretion, which are essential for determining its efficacy and safety profile. Epirizole may exhibit side effects common to NSAIDs, such as gastrointestinal discomfort or increased risk of bleeding, necessitating careful consideration in patients with certain health conditions. Overall, Epirizole is an important agent in pain management and inflammation control, contributing to the broader category of therapeutic options available in clinical practice.

Formula: C₁₁H₁₄N₄O₂

InChI: InChI=1/C10H12N4O2/c1-7-6-9(16-3)14(13-7)10-11-5-4-8(12-10)15-2/h4-6H,1-3H3

InChI key: InChIKey=RHAXSHUQNIEUEY-UHFFFAOYSA-N

SMILES: O(C)C=1N(C=2N=C(OC)C=C(C)N2)N=C(C)C1

Synonyms:

• 1-(4-Methoxy-6-methyl-2-pyrimidinyl)-3-methyl-5-methoxypyrazole
• 1-(4-Methyl-6-methoxy-2-pyrimidinyl)-3-methyl-5-methoxypyrazole
• 2-(3-Methoxy-5-methylpyrazol-2-yl)-4-methoxy-6-methylpyrimidine
• 2-(3-Methyl-5-methoxy-1-pyrazolyl)-4-methoxy-6-methylpyrimidine
• 4-Methoxy-2-(5-methoxy-3-methyl-1H-pyrazol-1-yl)-6-methylpyrimidine
• 4-Methoxy-2-(5-methoxy-3-methylpyrazol-1-yl)-6-methylpyrimidin
• 4-Methoxy-2-(5-methoxy-3-methylpyrazol-1-yl)-6-methylpyrimidin [German]
• 4-Methoxy-2-(5-methoxy-3-methylpyrazol-1-yl)-6-methylpyrimidine
• 4-methoxy-2-(5-methoxy-3-methyl-1H-pyrazol-1-yl)pyrimidine
• Brn 0751084
• Da-398
• Epirizol
• Epirizol [INN-Spanish]
• Epirizole [USAN:INN:JAN]
• Epirizolum
• Epirizolum [INN-Latin]
• Mebron
• Mepirizol
• Mepirizol [German]
• Mepirizole
• Pyrimidine, 4-methoxy-2-(5-methoxy-3-methyl-1H-pyrazol-1-yl)-6-methyl-
• Pyrimidine, 4-methoxy-2-(5-methoxy-3-methylpyrazol-1-yl)-6-methyl-
• Unii-3B46O2Fh8I
• Epirizole
• 5-25-18-00012 (Beilstein Handbook Reference)
• 2-(5-methoxy-3-methyl-1-pyrazinyl)-4-methoxy-6-methyl-pyrimidine

Pyrimidine,4-methoxy-2-(5-methoxy-3-methyl-1H-pyrazol-1-yl)-6-methyl-

CAS: 18694-40-1

Formula: C₁₁H₁₄N₄O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 234.2545

Ref: IN-DA00I1U8

Epirizole

CAS: 18694-40-1

Epirizole

Purity: ≥98%

Molecular weight: 234.25g/mol

Ref: 54-BUP14198

Mepirizole

CAS: 18694-40-1

Formula: C₁₀H₁₂N₄O₂

Molecular weight: 220.23

Ref: 7W-GP4791

Mepirizole

Controlled Product

CAS: 18694-40-1

Applications Mepirizole induces precocious differentiation of insulin-producing ti-cells in larval zebrafish. Also, it increases the expression of MDR1 mRNA in Caco-2 cells; Non-acidic analgesic.
References Rovira, M., et al.: Proc. Natl. Acad. Sci. U.S.A., 108, 19264-19269 (2011); Takara, K., et al.: Drug Chem. Toxicol., 32, 332-337 (2009); Yang, S., et al.: J. Pharm. Sci., 106, 249-256 (2008);

Formula: C₁₁H₁₄N₄O₂

Color and Shape: White To Off-White

Molecular weight: 234.25

Ref: TR-M225093

Epirizole

CAS: 18694-40-1

Epirizole (Mebron) shows antipyretic, analgesic, and anti-inflammatory activity and can be used in studies about chronic rheumatoid arthritis.

Formula: C₁₁H₁₄N₄O₂

Purity: 99.96%

Color and Shape: Solid

Molecular weight: 234.25

Ref: TM-T19641