CAS 18710-27-5

Homoglutathione

Description:

Homoglutathione, with the CAS number 18710-27-5, is a naturally occurring tripeptide that is structurally similar to glutathione, consisting of the amino acids gamma-glutamate, cysteine, and glycine. It is primarily found in certain plants and microorganisms and plays a crucial role in cellular processes, including antioxidant defense, detoxification, and regulation of cellular redox status. Homoglutathione exhibits properties that allow it to scavenge free radicals, thereby protecting cells from oxidative stress. Its structure features a gamma linkage between the glutamate and cysteine residues, which distinguishes it from conventional glutathione. This compound is of interest in various fields, including biochemistry and pharmacology, due to its potential therapeutic applications and its role in plant physiology. Additionally, homoglutathione may influence metabolic pathways and contribute to the overall health of organisms that produce or utilize it. Research continues to explore its functions and benefits, particularly in relation to stress responses and disease prevention.

Formula: C₁₁H₁₉N₃O₆S

InChI: InChI=1S/C11H19N3O6S/c12-6(11(19)20)1-2-8(15)14-7(5-21)10(18)13-4-3-9(16)17/h6-7,21H,1-5,12H2,(H,13,18)(H,14,15)(H,16,17)(H,19,20)/t6-,7-/m0/s1

InChI key: InChIKey=HKBNQXMLSMKLJV-BQBZGAKWSA-N

SMILES: [C@H](C(NCCC(O)=O)=O)(NC(CC[C@@H](C(O)=O)N)=O)CS

Synonyms:

• <span class="text-smallcaps">L</smallcap>-γ-Glutamyl-<smallcap>L</span>-cysteinyl-β-alanine
• Glutamine, N-[1-[(2-carboxyethyl)carbamoyl]-2-mercaptoethyl]-
• Glutamine, N-[1-[(2-carboxyethyl)carbamoyl]-2-mercaptoethyl]-, <span class="text-smallcaps">L</span>-
• Homoglutathione
• β-Alanine, <span class="text-smallcaps">L</smallcap>-γ-glutamyl-<smallcap>L</span>-cysteinyl-
• β-Alanine, N-(N-<span class="text-smallcaps">L</smallcap>-γ-glutamyl-<smallcap>L</span>-cysteinyl)-
• Glutamine, N-[1-[(2-carboxyethyl)carbamoyl]-2-mercaptoethyl]-, L-
• L-γ-Glutamyl-L-cysteinyl-β-alanine
• β-Alanine, L-γ-glutamyl-L-cysteinyl-
• β-Alanine, N-(N-L-γ-glutamyl-L-cysteinyl)-

Homoglutathione

CAS: 18710-27-5

Homoglutathione is a taste-modifying peptide responsible (in combination with γ-glutamyl peptides as γ-Glu-Leu and γ-Glu-Val for the “kokumi” flavor. Pesticides containing electrophilic centers can be metabolized in legumes via conjugation to homoglutathione or glutathione.

Formula: C₁₁H₁₉N₃O₆S

Purity: 91.4%

Color and Shape: White Powder

Molecular weight: 321.35

Ref: 01-4027578

Homoglutathione H-Glu(Cys-b-Ala-OH)-OH trifluroacetate

CAS: 18710-27-5

Please enquire for more information about Homoglutathione H-Glu(Cys-b-Ala-OH)-OH trifluroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₁₁H₁₉N₃O₆S•(C₂HF₃O₂)x

Purity: Min. 95%

Ref: 3D-BH184303

Homoglutathione H-Glu(Cys-β-Ala-OH)-OH TFA Salt

CAS: 18710-27-5

Applications Homoglutathione H-Glu(Cys-β-Ala-OH)-OH (cas# 18710-27-5) is a useful research chemical.

Formula: C₁₁H₁₉N₃O₆S·x(C₂HF₃O₂)

Color and Shape: Neat

Molecular weight: 321.35 + x(114.02)

Ref: TR-H593508

Homoglutathione H-Glu(Cys-b-Ala-OH)-OH

CAS: 18710-27-5

Homoglutathione is a glutathione analog that contains an extra b-alanine residue. Homoglutathione has been shown to be a potent inhibitor of fatty acid synthesis. It inhibits the activity of the enzyme, acetyl-CoA carboxylase, which catalyzes the conversion of acetyl-CoA to malonyl-CoA. Homoglutathione also binds to and inhibits cytoplasmic proteins, such as glutamine synthetase and glutamate synthase. The binding of homoglutathione to these proteins prevents the formation of the active site by preventing the hydrogen bonding between amino acid residues. This process is important in energy metabolism because it regulates the production of ATP from ADP and phosphate.

Formula: C₁₁H₁₉N₃O₆S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 321.35 g/mol

Ref: 3D-FH109127