CAS 187100-75-0

myristoyl coenzyme A

Description:

Myristoyl coenzyme A (CAS 187100-75-0) is a fatty acyl-CoA derivative, specifically the CoA thioester of myristic acid, a saturated fatty acid with a 14-carbon chain. This compound plays a crucial role in various biochemical pathways, particularly in lipid metabolism and the synthesis of complex lipids. Myristoyl CoA is involved in the post-translational modification of proteins, where it acts as a lipid anchor, facilitating membrane association and influencing protein function. It is also a substrate for enzymes involved in fatty acid elongation and desaturation processes. The compound is characterized by its high reactivity due to the thioester bond, which can be hydrolyzed to release myristic acid and CoA. Myristoyl CoA is typically found in cellular compartments such as the cytosol and mitochondria, where it participates in metabolic pathways essential for energy production and cellular signaling. Its role in cellular processes underscores its importance in both normal physiology and various disease states, including metabolic disorders.

Formula: C₃₅H₆₂N₇O₁₇P₃S

Myristoyl coenzyme A lithium

CAS: 187100-75-0

Myristoyl coenzyme A lithium, a compound marked by lithium in its myristoylated form, plays a crucial role in the biochemical mechanism of myristoylation, essential for both viral functionalities and tumor growth in colon epithelial cells. This process is predominantly governed by N-myristoyltransferase (NMT), which exhibits increased activity in colon epithelial tumors compared to normal cells. The activity of NMT is significantly influenced by the reduction of coenzyme A (CoA), a vital regulator that enhances NMT's ability to induce myristoylation, unlike its oxidized form which impedes this process. Consequently, Myristoyl coenzyme A serves as an inhibitor to the demyristoylation activity, showcasing its potential as an anticancer and antiviral agent.

Formula: C₃₅H₆₃LiN₇O₁₇P₃S

Color and Shape: Solid

Molecular weight: 985.3374

Ref: TM-T84743

Myristoyl Coenzyme A, Lithium salt

CAS: 187100-75-0

Purity: 95%

Molecular weight: 981.307

Ref: 10-C300049

Myristoyl coenzyme A lithium salt

CAS: 187100-75-0

Myristoyl coenzyme A lithium salt is an activator that can be used in the synthesis of Ribonucleosides and Deoxyribonucleosides. It has a high purity, which ensures high quality synthesis. Myristoyl coenzyme A lithium salt is a novel nucleotide precursor that can be used to synthesize DNA or RNA for use in anti-cancer or antiviral treatments.

Formula: C₃₅H₆₂N₇O₁₇P₃S·xLi

Purity: Min. 95%

Molecular weight: 977.89 g/mol

Ref: 3D-NM63223