CAS 18725-37-6

N,S-Diacetylcysteine

Description:

N,S-Diacetylcysteine (DAC) is a derivative of the amino acid cysteine, characterized by the presence of two acetyl groups attached to the nitrogen and sulfur atoms of the cysteine backbone. This compound is known for its antioxidant properties and potential therapeutic applications, particularly in respiratory diseases and as a mucolytic agent. DAC is soluble in water and exhibits stability under physiological conditions, making it suitable for various formulations. Its structure allows it to participate in redox reactions, contributing to its role in cellular defense mechanisms against oxidative stress. Additionally, N,S-Diacetylcysteine may enhance the bioavailability of cysteine, promoting the synthesis of glutathione, a critical antioxidant in the body. The compound is generally considered safe, but like any chemical, it should be handled with care, following appropriate safety guidelines. Research continues to explore its full potential in clinical applications, particularly in the context of chronic obstructive pulmonary disease (COPD) and other conditions associated with oxidative damage.

Formula: C₇H₁₁NO₄S

InChI: InChI=1S/C7H11NO4S/c1-4(9)8-6(7(11)12)3-13-5(2)10/h6H,3H2,1-2H3,(H,8,9)(H,11,12)/t6-/m0/s1

InChI key: InChIKey=HSPYGHDTVQJUDE-LURJTMIESA-N

SMILES: [C@@H](CSC(C)=O)(NC(C)=O)C(O)=O

Synonyms:

• (2R)-3-(Acetylsulfanyl)-2-acetamidopropanoic acid
• <span class="text-smallcaps">L</span>-Cysteine, N,S-diacetyl-
• <span class="text-smallcaps">L</span>-Cysteine, N-acetyl-, acetate (ester)
• Acetic acid, thio-, S-ester with N-acetyl-<span class="text-smallcaps">L</span>-cysteine
• Cysteine, N-acetyl-, acetate
• Cysteine, N-acetyl-, acetate (ester), <span class="text-smallcaps">L</span>-
• Dacisteina
• Dacisteina [Spanish]
• Dacisteine [INN]
• Dacisteinum
• Dacisteinum [Latin]
• N,S-Diacetyl-<span class="text-smallcaps">L</span>-cysteine
• N,S-Diacetylcysteine
• N,S-diacetyl-L-cysteine
• N-Acetyl-L-cysteine, acetate (ester)
• N-Acetylcysteine S-acetate
• Unii-Wf970Atw3T
• L-Cysteine, N-acetyl-, acetate (ester)
• Acetic acid, thio-, S-ester with N-acetyl-L-cysteine
• Cysteine, N-acetyl-, acetate (ester), L-

ACETYLCYSTEINE IMPURITY D CRS

CAS: 18725-37-6

ACETYLCYSTEINE IMPURITY D CRS

Formula: C₇H₁₁NO₄S

Molecular weight: 205.2315

Ref: 41-A0153000

Acetylcysteine Related Compound D (N,S-Diacetyl-L-Cysteine)

CAS: 18725-37-6

Other organo-sulfur acid compounds

Formula: C₇H₁₁NO₄S

Color and Shape: White Solid

Molecular weight: 205.04088

Ref: 45-1009049

Dacisteine

CAS: 18725-37-6

Formula: C₇H₁₁NO₄S

Purity: 97%

Color and Shape: Solid

Molecular weight: 205.2315

Ref: IN-DA00ABZ8

Acetylcysteine EP Impurity D (Acetylcysteine USP Related Compound D)

CAS: 18725-37-6

Formula: C₇H₁₁NO₄S

Molecular weight: 205.23

Ref: 4Z-A-336002

(R)-2-Acetamido-3-(Acetylthio)Propanoic Acid

CAS: 18725-37-6

(R)-2-Acetamido-3-(Acetylthio)Propanoic Acid

Purity: 98%

Molecular weight: 205.23g/mol

Ref: 54-OR1008469

Dacisteine

CAS: 18725-37-6

Dacisteine

Purity: ≥98%

Molecular weight: 205.23g/mol

Ref: 54-BUP11269

N,S-Diacetyl-L-cysteine

Controlled Product

CAS: 18725-37-6

Formula: C₇H₁₁NO₄S

Color and Shape: Neat

Molecular weight: 205.23

Ref: 86-MM0024.01

N,S-Diacetyl-L-cysteine

CAS: 18725-37-6

Impurity Acetylcysteine EP Impurity D
Applications N,S-Diacetyl-L-cysteine (Acetylcysteine EP Impurity D) is a double-prodrugs of L-cysteine: differential protection against acetaminophen-induced hepatotoxicity in mice (1,2,3).
References (1) Vina, J., et al.: Biochem. J., 170, 627 (1978) (2) Roberts, J., et al.: J. Med. Chem., 30, 1891 (1987) (3) Nagasawa, H., et al.: J. Biochem. Toxicol., 11, 289 (1996)

Formula: C₇H₁₁NO₄S

Color and Shape: White To Off-White

Molecular weight: 205.23

Ref: TR-D312300

Acetylcysteine EP Impurity D

CAS: 18725-37-6

Formula: C₇H₁₁NO₄S

Molecular weight: 205.23

Ref: ST-EA-CP-A79004

(2R)-2-Acetamido-3-acetylsulfanyl-propanoic acid

CAS: 18725-37-6

2-Acetamido-3-acetylsulfanylpropanoic acid is a pharmaceutical preparation that has been shown to have antitumor activity in cell lines derived from human breast, colon, lung, and prostate cancer. It has been shown to inhibit the growth of tumour cells by inducing apoptosis. The mechanism of action may be due to its ability to bind with fatty alcohols and hydroxyapatite in the acidic environment of cancer cells. This binding prevents the formation of fatty acid radicals and cancerous substances. 2-Acetamido-3-acetylsulfanylpropanoic acid also has anticancer activity when it is used on cell lines derived from human colorectal carcinoma.

Formula: C₇H₁₁NO₄S

Purity: Min. 95 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 205.23 g/mol

Ref: 3D-FA138843

(R)-2-Acetamido-3-(acetylthio)propanoic acid

CAS: 18725-37-6

Purity: 97%

Color and Shape: Solid

Molecular weight: 205.2299957

Ref: 10-F868799

Dacisteine

CAS: 18725-37-6

Dacisteine (N,S-Diacetyl-L-cysteine) is an inhibitor of New Delhi metallo-beta-lactamase-1 (NDM-1, IC50 = 1000 μM).

Formula: C₇H₁₁NO₄S

Purity: 99.57%

Color and Shape: Solid

Molecular weight: 205.23

Ref: TM-T15047

Acetylcysteine EP Impurity D (Acetylcysteine USP Related Compound D)

CAS: 18725-37-6

Formula: C₇H₁₁NO₄S

Color and Shape: White To Off-White Solid

Molecular weight: 205.23

Ref: 4Z-C-772