CAS 187269-60-9

Bimosiamose disodium

Description:

Bimosiamose disodium, with the CAS number 187269-60-9, is a synthetic oligosaccharide that is primarily recognized for its role as a pharmacological agent. It is characterized by its disodium salt form, which enhances its solubility in aqueous solutions, making it suitable for various biological applications. Bimosiamose is known for its potential immunomodulatory effects, particularly in the context of enhancing immune responses. The substance is often studied for its interactions with specific receptors and its ability to influence cellular signaling pathways. In terms of stability, it is generally stable under standard laboratory conditions, although it may be sensitive to extreme pH levels or prolonged exposure to heat. As with many oligosaccharides, its biological activity can be influenced by its molecular structure, including the arrangement of its sugar units. Safety data indicates that it should be handled with care, following appropriate safety protocols, as with any chemical substance used in research or therapeutic contexts.

Formula: C₄₆H₅₂Na₂O₁₆

InChI: InChI=1/C46H54O16.2Na/c47-24-34-38(53)40(55)42(57)44(61-34)59-32-15-6-4-13-29(32)27-12-9-11-26(20-27)10-3-1-2-8-18-46(23-37(51)52)19-17-28(21-36(49)50)31(22-46)30-14-5-7-16-33(30)60-45-43(58)41(56)39(54)35(25-48)62-45;;/h1-2,4-7,9,11-17,20,22,34-35,38-45,47-48,53-58H,3,8,10,18-19,21,23-25H2,(H,49,50)(H,51,52);;/q;2*+1/p-2/b2-1+;;/t34-,35-,38-,39-,40+,41+,42+,43+,44+,45+,46?;;/m1../s1

SMILES: C(=CCCC1(CC=C(CC(=O)O)C(=C1)c1ccccc1OC1C(C(C(C(CO)O1)O)O)O)CC(=O)O)CCc1cccc(c1)c1ccccc1OC1C(C(C(C(CO)O1)O)O)O.[Na].[Na]

Synonyms:

• Bimosiamose disodium [USAN]
• (1,1'-Biphenyl)-3-acetic acid, 3',3'''-(1,6-hexanediyl)bis(6'-(alpha-D-mannopyranosyloxy)-, disodium salt
• Disodium 3',3'''-hexamethylenebis(6'-alpha-D-mannopyranosyloxy)-3-biphenylacetate)
• TBC1269z
• Unii-7Ak2Fkb9Aw
• (1,1'-Biphenyl)-3-acetic acid, 3',3'''-(1,6-hexanedidyl)bis(6'-(alpha-D-mannopyranosyloxy)-, disodium salt
• disodium 2,2'-(4-{(3E)-6-[2'-(alpha-D-mannopyranosyloxy)biphenyl-3-yl]hex-3-en-1-yl}-6-[2-(alpha-D-mannopyranosyloxy)phenyl]cyclohexa-1,5-diene-1,4-diyl)diacetate

Bimosiamose disodium

CAS: 187269-60-9

Bimosiamose disodium (TBC-1269Z), a pan-selectin inhibitor, has IC50s: E-selectin 88 μM, P-selectin 20 μM, L-selectin 86 μM; anti-inflammatory.

Formula: C₄₆H₅₂Na₂O₁₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 906.88

Ref: TM-T14573