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CAS 187283-25-6

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FMOC-L-PHE(4-GUANIDINO-BOC2)-OH

Description:
FMOC-L-PHE(4-GUANIDINO-BOC2)-OH is a specialized amino acid derivative commonly used in peptide synthesis and research. It features a 9-fluorenylmethoxycarbonyl (FMOC) protecting group, which is widely employed to protect the amino group during the synthesis of peptides. The compound contains a phenylalanine (PHE) backbone, modified with a guanidino group at the para position, enhancing its potential for interactions in biological systems. The presence of the BOC (tert-butyloxycarbonyl) group further provides protection for the carboxylic acid functionality, allowing for selective reactions. This compound is typically utilized in the development of peptide-based therapeutics and in the study of protein interactions due to its unique structural properties. Its solubility and stability are influenced by the protecting groups, making it suitable for various synthetic methodologies. Overall, FMOC-L-PHE(4-GUANIDINO-BOC2)-OH is a valuable tool in the field of medicinal chemistry and peptide design.
Formula:C35H40N4O8
InChI:InChI=1/C35H40N4O8/c1-34(2,3)46-32(43)38-30(39-33(44)47-35(4,5)6)36-22-17-15-21(16-18-22)19-28(29(40)41)37-31(42)45-20-27-25-13-9-7-11-23(25)24-12-8-10-14-26(24)27/h7-18,27-28H,19-20H2,1-6H3,(H,37,42)(H,40,41)(H2,36,38,39,43,44)/t28-/m0/s1
SMILES:CC(C)(C)OC(=O)N=C(Nc1ccc(cc1)C[C@@H](C(=O)O)N=C(O)OCC1c2ccccc2c2ccccc12)N=C(O)OC(C)(C)C
Synonyms:
  • N-Alpha-(9-Fluorenylmethyloxycarbonyl)-L-4-Bis(Tert-Butyloxycarbonyl)Guanidino-Phenylalanine
  • Fmoc-Phe(4-Guanidino-Boc2)-Oh
  • Fmoc-Phe(4-Boc(T2)-Guanidino)-Oh
  • N-Alpha-(9-Fluorenylmethyloxycarbonyl)-L-4-Bis(T-Butyloxycarbonyl)Guanidino-Phenylalanine
  • N-Alpha-(9-Fluoroenylmethyloxycarbonyl)-L-4-Bis(T-Butyloxycarbonyl)Guanidino-Phenylalanine
  • 4-[N',N''-bis(tert-butoxycarbonyl)carbamimidamido]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine
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