CAS 1873306-74-1

5'-DMT-N4-Ac-5-Me-dC Phosphoramidite

Description:

5'-DMT-N4-Ac-5-Me-dC Phosphoramidite is a specialized chemical compound used primarily in the field of nucleic acid chemistry, particularly in the synthesis of oligonucleotides. This compound features a 5'-dimethoxytrityl (DMT) protecting group, which is crucial for the selective protection of the 5' hydroxyl group during the synthesis process. The N4-acetyl modification enhances the stability and solubility of the nucleoside, while the 5-methyl substitution at the cytosine base contributes to its unique properties, such as increased binding affinity and altered hybridization characteristics. The phosphoramidite functional group allows for efficient coupling reactions in automated DNA synthesis, facilitating the formation of phosphodiester bonds between nucleotides. Overall, this compound is valuable for researchers working on DNA/RNA synthesis, gene therapy, and molecular diagnostics, as it enables the creation of modified oligonucleotides with tailored functionalities for various applications in biotechnology and medicine.

Formula: C₄₂H₅₂N₅O₈P

Synonyms:

• 5'-DMT-N4-Ac-5-Me-dC Phosphoramidite
• 5'-O-DMT-N4-Acetyl-5-Methyl-2'-deoxycytidine 3'-CE phosphoramidite
• 5-Me-dC(Ac) amidite
• 5'-O-DMT-N4-Acetyl-2'-Deoxy-5-methycytidine-CE Phosphor amidite

N4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite

CAS: 1873306-74-1

Formula: C₄₂H₅₂N₅O₈P

Purity: 98%

Color and Shape: Solid

Molecular weight: 785.8647

Ref: IN-DA01LHZ7

5-Me-dC(Ac) amidite

CAS: 1873306-74-1

5-Me-dC(Ac) amidite

Purity: 97%

Molecular weight: 785.86g/mol

Ref: 54-OR1035579

N4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite

CAS: 1873306-74-1

N4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite is a novel nucleoside and deoxyribonucleoside that has been synthesized by the chemical modification of cytidine. It is an anticancer drug and antiviral agent, which has been shown to activate DNA polymerase, inhibit RNA synthesis and have antiviral activities against HIV, HSV, CMV, and VZV. N4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite has high purity with low impurities (0.1% DMSO), making it a valuable nucleoside for use in synthesis of ribonucleotide analogues.

Formula: C₄₂H₅₂N₅O₈P

Purity: Min. 97 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 785.86 g/mol

Ref: 3D-PA46085

5-Me-dC(Ac) amidite

CAS: 1873306-74-1

Purity: 97%

Molecular weight: 785.879

Ref: 10-F987555

N4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite

Controlled Product

CAS: 1873306-74-1

Applications N4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite (CAS# 1873306-74-1) is a useful research chemical compound.

Formula: C₄₂H₅₂N₅O₈P

Color and Shape: Neat

Molecular weight: 785.865

Ref: TR-N210855