CAS 18742-02-4

2-(2-Bromoethyl)-1,3-dioxolane

Description:

2-(2-Bromoethyl)-1,3-dioxolane is a chemical compound characterized by its unique structure, which includes a dioxolane ring and a bromoethyl substituent. This compound typically appears as a colorless to pale yellow liquid and is known for its reactivity due to the presence of the bromine atom, which can participate in nucleophilic substitution reactions. The dioxolane ring contributes to the compound's stability and solubility in organic solvents. It is often used as an intermediate in organic synthesis, particularly in the preparation of various pharmaceuticals and agrochemicals. The presence of the bromine atom also makes it a useful reagent in cross-coupling reactions. Safety considerations are important when handling this compound, as brominated compounds can be hazardous. Proper storage and handling procedures should be followed to minimize exposure and ensure safety in laboratory settings. Overall, 2-(2-Bromoethyl)-1,3-dioxolane is a versatile compound with significant applications in synthetic organic chemistry.

Formula: C₅H₉BrO₂

InChI: InChI=1S/C5H9BrO2/c6-2-1-5-7-3-4-8-5/h5H,1-4H2

InChI key: InChIKey=GGZQLTVZPOGLCC-UHFFFAOYSA-N

SMILES: C(CBr)C1OCCO1

Synonyms:

• 1,1-(Ethylenedioxy)-3-bromopropane
• 1,3-Dioxolan-2-ylethyl bromide
• 1,3-Dioxolane, 2-(2-bromoethyl)-
• 1-Bromo-3,3-(ethylenedioxy)propane
• 2-(1,3-Dioxolan-2-yl)ethyl bromide
• 2-(2-Bromoethyl)-1,3-Dioxalane
• 2-(2-Bromoethyl)-1,3-dioxolan
• 3,3-(Ethylenedioxy)propyl bromide
• 3-Bromopropanal ethylene acetal
• 3-Bromopropionaldehyde ethylene acetal
• β-Bromopropionaldehyde ethylene acetal

2-(2-Bromoethyl)-1,3-dioxolane

CAS: 18742-02-4

Formula: C₅H₉BrO₂

Purity: >90.0%(GC)

Color and Shape: Colorless to Light orange to Yellow clear liquid

Molecular weight: 181.03

Ref: 3B-B1132

2-(2-Bromoethyl)-1,3-Dioxolane

CAS: 18742-02-4

Formula: C₅H₉BrO₂

Purity: 97.00%

Color and Shape: Liquid, Clear

Molecular weight: 181.029

Ref: 10-F049739

2-(2-Bromoethyl)-1,3-dioxolane, 95%, stab. with silver

CAS: 18742-02-4

2-(2-Bromoethyl)-1,3-dioxolane is used as a pharmaceutical intermediate, dioxolanes, acetals, ketals, building blocks, chemical synthesis, organic building blocks and oxygen compounds. 1,1-(Ethylenedioxy)-3-bromopropane is used in the synthesis of EGFR inhibitors. Also used in the synthesis of oral

Formula: C₅H₉BrO₂

Purity: 95%

Color and Shape: Liquid, Clear colorless to yellow or pale brown

Molecular weight: 181.03

Ref: 02-A11441

2-(2-Bromoethyl)-1,3-dioxolane, Tech grade

CAS: 18742-02-4

Formula: C₅H₉BrO₂

Purity: 96%

Color and Shape: Liquid

Molecular weight: 181.0278

Ref: IN-DA0032UH

2-(2-Bromoethyl)-1,3-dioxolane

CAS: 18742-02-4

2-(2-Bromoethyl)-1,3-dioxolane

Formula: C₅H₉BrO₂

Purity: ≥95%

Color and Shape: colourless liquid

Molecular weight: 181.03g/mol

Ref: 54-OR52533

2-(2-Bromoethyl)-1,3-dioxolane

CAS: 18742-02-4

Formula: C₅H₉BrO₂

Purity: ≥ 95.0%

Color and Shape: Clear, colourless to pale yellow liquid

Molecular weight: 181.04

Ref: 7W-GK3738

1,1-(Ethylenedioxy)-3-bromopropane

Controlled Product

CAS: 18742-02-4

Applications 1,1-(Ethylenedioxy)-3-bromopropane is used in the synthesis of EGFR inhibitors. Also used in the synthesis of orally active agents of cancer and cell proliferation with quinoline substructures.
References Zhang, X. et al.: Arch. Pharm., 346, 44 (2013); Lee, Y. et al.: J. Med. Chem., 55, 10363 (2012);

Formula: C₅H₉BrO₂

Color and Shape: Neat

Molecular weight: 181.03

Ref: TR-E678630

2-(2-Bromoethyl)-1,3-dioxolane

CAS: 18742-02-4

2-(2-Bromoethyl)-1,3-dioxolane is a synthetic chemical compound that is used for the asymmetric synthesis of fatty acids. It can be prepared by the cross-coupling reaction of ethyl formate with bromoethane and copper(II) acetate in trifluoroacetic acid. The reaction produces an unsymmetrical product with two aldehyde groups and two halides on each side of the molecule. It can also be prepared by the reaction of 2-bromoethanol with sodium formaldehyde sulfoxylate and sodium methoxide in methanol. This process produces a symmetrical molecule with one aldehyde group on each side of the molecule. 2-(2-Bromoethyl)-1,3-dioxolane has been shown to have anti-cancer properties in carcinoma cell lines.

Formula: C₅H₉BrO₂

Purity: Min. 95%

Color and Shape: Brown Colorless Yellow Clear Liquid

Molecular weight: 181.03 g/mol

Ref: 3D-FB35778