As of my last update in October 2023, AM-6494, identified by the CAS number 1874232-80-0, is a chemical compound that has garnered interest in the field of medicinal chemistry, particularly for its potential therapeutic applications. While specific characteristics such as molecular formula, structure, and detailed physical properties may not be widely available in public databases, compounds like AM-6494 are typically evaluated for their biological activity, solubility, stability, and pharmacokinetic properties. Researchers often investigate such compounds for their interactions with biological targets, which can include enzymes or receptors, to assess their efficacy and safety profiles. The development of AM-6494 may involve synthetic routes, characterization techniques like NMR and mass spectrometry, and biological assays to determine its potential as a drug candidate. For the most accurate and detailed information, consulting scientific literature or databases that specialize in chemical substances is recommended.

AM-6494 is a Potent and Orally Efficacious β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor with in Vivo Selectivity over BACE2.

AM-6494

1874232-80-0: As of my last update in October 2023, AM-6494, identified by the CAS number 1874232-80-0, is a chemical compound that has garnered interest in the field of medicinal chemistry, particularly for its potential therapeutic applications. While specific characteristics such as molecular formula, structure, and detailed physical properties may not be widely available in public databases, compounds like AM-6494 are typically evaluated for their biological activity, solubility, stability, and pharmacokinetic properties. Researchers often investigate such compounds for their interactions with biological targets, which can include enzymes or receptors, to assess their efficacy and safety profiles. The development of AM-6494 may involve synthetic routes, characterization techniques like NMR and mass spectrometry, and biological assays to determine its potential as a drug candidate. For the most accurate and detailed information, consulting scientific literature or databases that specialize in chemical substances is recommended.

<p>AM-6494 is a potent and orally active BACE1 inhibitor (IC50: 0.4 nM) with in vivo selectivity over BACE2 (IC50: 18.6 nM).</p>

CAS 1874232-80-0

AM-6494

AM-6494

Ref: TM-T10292