CAS 187618-60-6

N5-[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-ornithine

Description:

The chemical substance known as N5-[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-ornithine, with the CAS number 187618-60-6, is a complex organic compound characterized by its intricate structure that includes a D-ornithine backbone, a sulfonamide group, and various aromatic and aliphatic substituents. This compound features a benzofuran moiety, which contributes to its potential biological activity, and a fluorenylmethoxycarbonyl (Fmoc) protecting group, commonly used in peptide synthesis. The presence of multiple methyl groups enhances its lipophilicity, potentially influencing its solubility and interaction with biological membranes. The sulfonylamino group suggests possible applications in medicinal chemistry, particularly in the development of pharmaceuticals targeting specific biological pathways. Overall, the compound's unique structural features may confer specific properties that are of interest in research and development within the fields of biochemistry and pharmacology.

Formula: C₃₄H₄₀N₄O₇S

InChI: InChI=1S/C34H40N4O7S/c1-19-20(2)30(21(3)26-17-34(4,5)45-29(19)26)46(42,43)38-32(35)36-16-10-15-28(31(39)40)37-33(41)44-18-27-24-13-8-6-11-22(24)23-12-7-9-14-25(23)27/h6-9,11-14,27-28H,10,15-18H2,1-5H3,(H,37,41)(H,39,40)(H3,35,36,38)/t28-/m1/s1

InChI key: InChIKey=HNICLNKVURBTKV-MUUNZHRXSA-N

SMILES: C(OC(N[C@H](CCCNC(NS(=O)(=O)C=1C(C)=C2C(=C(C)C1C)OC(C)(C)C2)=N)C(O)=O)=O)C3C=4C(C=5C3=CC=CC5)=CC=CC4

Synonyms:

• (E)-N5-(amino{[(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]amino}methylidene)-N2-(tert-butoxycarbonyl)-D-ornithine
• <span class="text-smallcaps">D</span>-Ornithine, N⁵-[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N²-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• N'-[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-arginine
• N⁵-[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N²-[(9H-fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">D</span>-ornithine
• D-Ornithine, N5-[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• 1: PN: WO2022213118 TABLE: 12 claimed sequence
• N5-[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-ornithine

Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Nω-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-D-arginine

CAS: 187618-60-6

Formula: C₃₄H₄₀N₄O₇S

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 648.78

Ref: 3B-F0875

Fmoc-D-Arg(Pbf)-OH

CAS: 187618-60-6

Bachem ID: 4025744.

Formula: C₃₄H₄₀N₄O₇S

Purity: 99.9%

Color and Shape: White Powder

Molecular weight: 648.78

Ref: 01-4025744

D-Ornithine,N5-[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-

CAS: 187618-60-6

Formula: C₃₄H₄₀N₄O₇S

Purity: 97%

Color and Shape: Solid

Molecular weight: 648.7690

Ref: IN-DA00I1VL

Fmoc-D-Arg(Pbf)-OH

CAS: 187618-60-6

Fmoc-D-Arg(Pbf)-OH

Purity: 98%

Molecular weight: 648.77g/mol

Ref: 54-OR1013341

Fmoc-D-Arg(Pbf)-OH

CAS: 187618-60-6

Formula: C₃₄H₄₀N₄O₇S

Purity: ≥ 98.0%

Color and Shape: White to almost white powder or crystals

Molecular weight: 648.77

Ref: 7W-GM3013

Fmoc-D-Arg(Pbf)-OH

CAS: 187618-60-6

Formula: C₃₄H₄₀N₄O₇S

Molecular weight: 648.8

Ref: ST-EA-CP-L28024

Fmoc-D-Arg(Pbf)-OH

CAS: 187618-60-6

Fmoc-D-Arg(Pbf)-OH is a synthetic D-arginine peptide. It is an inhibitor of protein interactions, activator of ligand, and a research tool for receptor binding studies. Fmoc-D-Arg(Pbf)-OH has been used to characterize ion channels and antibody binding sites. This molecule has high purity with no impurities or traces of solvent.

Formula: C₃₄H₄₀N₄O₇S

Purity: Min. 95%

Molecular weight: 648.78 g/mol

Ref: 3D-FDR-1801-PI

Fmoc-D-Arg(Pbf)-OH

CAS: 187618-60-6

Fmoc-D-Arg(Pbf)-OH is a synthetic peptide that can inhibit the growth of cancer cells. It has been shown to inhibit protease activity in mitochondria and inhibit mitochondrial membrane potential. The uptake of Fmoc-D-Arg(Pbf)-OH by neutrophils is dependent on the presence of superparamagnetic iron nanoparticles, which are taken up by phagocytic cells and used for oxidative burst. Fmoc-D-Arg(Pbf)-OH has a high affinity for mammalian cells but not for bacterial or fungal cells.

Formula: C₃₄H₄₀N₄O₇S

Purity: Min. 95%

Molecular weight: 648.77 g/mol

Ref: 3D-FF40496

Fmoc-D-Arg(pbf)-OH

CAS: 187618-60-6

M06294 - Fmoc-D-Arg(pbf)-OH

Formula: C₃₄H₄₀N₄O₇S

Purity: 95%

Color and Shape: Solid, White powder

Molecular weight: 648.78

Ref: 10-M06294