CAS 1876467-74-1

BAY 1895344

CAS: 1876467-74-1

Formula: C₂₀H₂₁N₇O

Purity: 98%

Color and Shape: Solid

Molecular weight: 375.4270

Ref: IN-DA01DDTF

Elimusertib

CAS: 1876467-74-1

Elimusertib

Purity: ≥98%

Molecular weight: 375.43g/mol

Ref: 54-BUP12371

(R)-3-Methyl-4-(4-(1-Methyl-1H-Pyrazol-5-Yl)-8-(1H-Pyrazol-3-Yl)-1,7-Naphthyridin-2-Yl)Morpholine

CAS: 1876467-74-1

(R)-3-Methyl-4-(4-(1-Methyl-1H-Pyrazol-5-Yl)-8-(1H-Pyrazol-3-Yl)-1,7-Naphthyridin-2-Yl)Morpholine

Purity: 98%

Molecular weight: 375.43g/mol

Ref: 54-OR1022999

Elimusertib

CAS: 1876467-74-1

Elimusertib (BAY-1895344) is a potent, highly selective and orally available ATR inhibitor with an IC50 of 7 nM.Elimusertib shows potent anti-tumor efficacy in

Formula: C₂₀H₂₁N₇O

Purity: 98.72% - 99.84%

Color and Shape: Solid

Molecular weight: 375.43

Ref: TM-T7318

BAY-1895344

Controlled Product

CAS: 1876467-74-1

Applications BAY-1895344 is a selective ATR (ataxia-telangiectasia and Rad3 related protein) inhibitor used in the treatment of advanced hyperproliferative disease, prophylaxis, solid tumors and lymphomas.
References Wortmann, L., et al.: From PCT Int. Appl. (2016), WO 2016020320 A1 20160211

Formula: C₂₀H₂₁N₇O

Color and Shape: Neat

Molecular weight: 375.43

Ref: TR-B118925

BAY-1895344

CAS: 1876467-74-1

BAY-1895344 is an inhibitor of the CDK4 and CDK6 proteins, which are tumor-promoting enzymes that regulate cell cycle progression. BAY-1895344 has been evaluated in clinical studies for the treatment of cancer with promising results. This drug was also shown to increase epidermal growth factor (EGF) levels in vitro and to promote autophagy, a process whereby cells degrade their own components. In addition, this compound has been shown to have a positive effect on telomere length and tumor response in patients with squamous carcinoma.

Formula: C₂₀H₂₁N₇O

Purity: Min. 95%

Molecular weight: 375.43 g/mol

Ref: 3D-BB178556